The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease
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DOI: 10.1186/s40478-017-0425-9
Abstract: Rosenthal fibers (RFs) are cytoplasmic, proteinaceous aggregates. They are the pathognomonic feature of the astrocyte pathology in Alexander Disease (AxD), a neurodegenerative disorder caused by heterozygous mutations in the GFAP gene, encoding glial fibrillary acidic… read more here.
Keywords: rosenthal fibers; alexander disease; pathology; rfs ... See more keywords