Effects of metformin, rosiglitazone and insulin on bone metabolism in patients with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Bone"
DOI: 10.1016/j.bone.2018.04.004
Abstract: BACKGROUND Fracture risk is increased in individuals with type 2 diabetes (T2D). The pathophysiological mechanisms accentuating fracture risk in T2D are convoluted, incorporating factors such as hyperglycaemia, insulinopenia, and antidiabetic drugs. The objectives of this… read more here.
Keywords: insulin; metformin rosiglitazone; bone; type diabetes ... See more keywords
Rosiglitazone Phosphorylates Akt, Reduces Caspase 3 Activity and Enhances Mitochondrial Function in frozen Thawed Stallion Spermatozoa
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2018.05.047
Abstract: Spermatozoa surviving freezing thawing, experience changes that represent an acceleration of the default apoptotic dead pathway that the spermatozoa experience after ejaculation[1]. One key protein related to survival is the Akt, provided that this kinase… read more here.
Keywords: spermatozoa; mitochondrial function; thawed stallion; rosiglitazone ... See more keywords
Rosiglitazone Prevents Autophagy by Regulating Nrf2-Antioxidant Response Element in a Rat Model of Lithium-pilocarpine-induced Status Epilepticus
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2020.10.026
Abstract: Status epilepticus (SE) leads to irreversible neuronal damage and consists of a complex pathogenesis that involves oxidative stress and subsequent autophagy. Rosiglitazone has recently been considered as a potential neuroprotective factor in epilepsy because of… read more here.
Keywords: status epilepticus; pilocarpine induced; rosiglitazone; lithium pilocarpine ... See more keywords
Effects of intracerebroventricular injection of rosiglitazone on appetite-associated parameters in chicks.
Sign Up to like & getrecommendations! Published in 2017 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2015.12.021
Abstract: Rosiglitazone, a thiazolidinedione, is a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist that increases insulin sensitivity. A documented side effect of this diabetes drug is increased appetite, although the mechanism mediating this response is unknown. To… read more here.
Keywords: food intake; rosiglitazone appetite; rosiglitazone; injection ... See more keywords
Handheld Platform for Sensitive Rosiglitazone Detection: Immunosensor Based on a Time-Based Readout Device.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04957
Abstract: The detection of rosiglitazone (RSG) in food is of great importance since the excessive intake of RSG could cause adverse effects on the human body. Although liquid chromatography-mass spectrometry and gas chromatography-mass spectrometry are the… read more here.
Keywords: rosiglitazone; time; based readout; time based ... See more keywords
Anticancer Effect of Rosiglitazone, a PPAR-γ Agonist against Diethylnitrosamine-Induced Lung Carcinogenesis
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b04357
Abstract: Multiple effects on cancer cells are exerted by the peroxisome proliferator-activated receptor γ (PPAR-γ). Recent studies have shown that rosiglitazone, a synthetic PPAR-γ ligand, inhibits the growth of cells. This research was designed to assess… read more here.
Keywords: ppar; group; dena induced; induced lung ... See more keywords
Determination of Rosiglitazone by Direct Analysis in Real-Time Mass Spectrometry
Sign Up to like & getrecommendations! Published in 2017 at "Analytical Letters"
DOI: 10.1080/00032719.2016.1248245
Abstract: ABSTRACT The determination of rosiglitazone in dietary supplements by direct analysis in real-time mass spectrometry normally provides low repeatability. The [M+H]+ signal sharply decreased in the presence of strong-base and weak-acid ionic compounds because rosiglitazone… read more here.
Keywords: direct analysis; determination rosiglitazone; rosiglitazone; mass spectrometry ... See more keywords
Coadministration of metformin or spironolactone enhances efficacy of rosiglitazone in management of PCOS
Sign Up to like & getrecommendations! Published in 2019 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2019.1675044
Abstract: Abstract The aim of this study was to compare the efficacy and safety of adding metformin or spironolactone to rosiglitazone in women with polycystic ovary syndrome (PCOS). This is a prospective non-randomized study in a… read more here.
Keywords: three groups; coadministration metformin; spironolactone enhances; metformin spironolactone ... See more keywords
Haem oxygenase‐1 up‐regulation by rosiglitazone via ROS‐dependent Nrf2‐antioxidant response elements axis or PPARγ attenuates LPS‐mediated lung inflammation
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14465
Abstract: Haem oxygenase‐1 (HO‐1) is induced by thiazolidinediones including rosiglitazone and exerts anti‐inflammatory effects in various models. However, the molecular mechanisms underlying rosiglitazone‐induced HO‐1 expression remain largely unknown in human pulmonary alveolar epithelial cells (HPAEpiCs). read more here.
Keywords: haem oxygenase; regulation rosiglitazone; rosiglitazone; oxygenase regulation ... See more keywords
Abstract 1596: The promising recipe sorafenib rosiglitazone and adipogenesis inducers cocktail for in vitro hepatocellular carcinoma differentiation induction besiege carcinogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1596
Abstract: Aim: The present study is focusing on using sorafenib, rosiglitazone, and adipogenesis-inducers cocktail (Insulin, Dexamethasone and IBMX) as a combination treatment to induce hepatocellular carcinoma (HCC) cell lines differentiation into adipocyte functioning cells, a strategy… read more here.
Keywords: rosiglitazone; differentiation induction; differentiation; cocktail ... See more keywords
Rosiglitazone enhances the apoptotic effect of 5-fluorouracil in colorectal cancer cells with high-glucose-induced glutathione
Sign Up to like & getrecommendations! Published in 2019 at "Science Progress"
DOI: 10.1177/0036850419886448
Abstract: Colorectal cancer is one of the most prevalent noncommunicable diseases worldwide. 5-Fluorouracil is the mainstay of chemotherapy for colorectal cancer. Previously, we have demonstrated that high glucose diminishes the cytotoxicity of 5-fluorouracil by promoting cell… read more here.
Keywords: high glucose; fluorouracil; colorectal cancer; rosiglitazone ... See more keywords