Mechanism of neuronal activity and synaptic transmission in rostral ventrolateral medulla
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2017.04.010
Abstract: Rostral ventrolateral medulla (RVLM) plays an essential role in blood pressure homeostasis. This study was aimed to investigate the mechanism of neuronal activity and synaptic transmission in the RVLM. Medulla oblongata slices were carefully obtained… read more here.
Keywords: rostral ventrolateral; mechanism neuronal; ventrolateral medulla; receptor ... See more keywords
Depletion of rostral ventrolateral medullary catecholaminergic neurons impairs the hypoxic ventilatory response in conscious rats
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.03.031
Abstract: The stimuli that commonly activate the catecholaminergic C1 neurons (nociception, hypotension, and hypoxia) also increase breathing. Pharmacogenetic evidence suggests that catecholaminergic neurons regulate breathing. Therefore, we evaluated whether the loss of C1 cells affects cardiorespiratory… read more here.
Keywords: rostral ventrolateral; response; depletion rostral; ventrolateral medullary ... See more keywords
Upregulation of Nav1.6 expression in the rostral ventrolateral medulla of stress-induced hypertensive rats
Sign Up to like & getrecommendations! Published in 2018 at "Hypertension Research"
DOI: 10.1038/s41440-018-0105-6
Abstract: The rostral ventrolateral medulla (RVLM) plays a key role in mediating the development of stress-induced hypertension (SIH) by excitation and/or inhibition of sympathetic preganglionic neurons. The voltage-gated sodium channel Nav1.6 has been found to contribute… read more here.
Keywords: rostral ventrolateral; nav1 expression; ventrolateral medulla; stress induced ... See more keywords
Overexpression of NaV1.6 in the rostral ventrolateral medulla in rats mediates stress-induced hypertension via glutamate regulation
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2021.2007942
Abstract: ABSTRACT Background The rostral ventrolateral medulla (RVLM) plays a key role in mediating the development of stress-induced hypertension (SIH). Furthermore, enhanced glutamate transport within glutamatergic neurons in the RVLM mediates pressor responses. Data from our… read more here.
Keywords: stress; glutamate; hypertension; expression ... See more keywords
IFN-γ deficiency in the rostral ventrolateral medulla contributes to stress-induced hypertension by impairing microglial synaptic engulfment.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of hypertension"
DOI: 10.1097/hjh.0000000000003470
Abstract: BACKGROUND Dysfunctional neurons and microglia in the rostral ventrolateral medulla (RVLM) have been implicated in the pathogenesis of stress-induced hypertension (SIH). Functional perturbation of microglial synaptic engulfment can induce aberrant brain circuit activity. IFN-γ is… read more here.
Keywords: synaptic engulfment; engulfment; hypertension; microglial synaptic ... See more keywords
BDNF-related mechanisms of neuroplasticity in the rostral ventrolateral medulla of sedentary versus active rats
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731939
Abstract: Overactivity of the sympathetic nervous system is implicated in cardiovascular disease (CVD), the leading cause of death. Sympathetic nerve activity is regulated by a region in the brainstem, the rostral ventrolateral medulla (RVLM). The RVLM… read more here.
Keywords: active rats; sedentary active; neuroplasticity; rostral ventrolateral ... See more keywords
The Cardiovascular Effect of Systemic Homocysteine Is Associated with Oxidative Stress in the Rostral Ventrolateral Medulla
Sign Up to like & getrecommendations! Published in 2017 at "Neural Plasticity"
DOI: 10.1155/2017/3256325
Abstract: It has been demonstrated that homocysteine (HCY) is a significant risk factor of hypertension, which is characterized by overactivity of sympathetic tone. Excessive oxidative stress in the rostral ventrolateral medulla (RVLM), a key region for… read more here.
Keywords: stress rostral; rostral ventrolateral; ventrolateral medulla; stress ... See more keywords
Neuroinflammation contributes to autophagy flux blockage in the neurons of rostral ventrolateral medulla in stress-induced hypertension rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-0942-2
Abstract: BackgroundNeuroinflammation plays hypertensive roles in the uninjured autonomic nuclei of the central nervous system, while its mechanisms remain unclear. The present study is to investigate the effect of neuroinflammation on autophagy in the neurons of… read more here.
Keywords: sih rats; neurons rostral; rostral ventrolateral; induced hypertension ... See more keywords
Mapping and Analysis of the Connectome of Sympathetic Premotor Neurons in the Rostral Ventrolateral Medulla of the Rat Using a Volumetric Brain Atlas
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2017.00009
Abstract: Spinally projecting neurons in the rostral ventrolateral medulla (RVLM) play a critical role in the generation of vasomotor sympathetic tone and are thought to receive convergent input from neurons at every level of the neuraxis;… read more here.
Keywords: neurons rostral; rostral ventrolateral; ventrolateral medulla; sympathetic premotor ... See more keywords
Sedentary Conditions Promote Subregionally Specific Changes in Brain-Derived Neurotrophic Factor in the Rostral Ventrolateral Medulla
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.756542
Abstract: A sedentary lifestyle is the top preventable cause of death and accounts for substantial socioeconomic costs to society. The rostral ventrolateral medulla regulates blood pressure under normal and pathophysiological states, and demonstrates inactivity-related structural and… read more here.
Keywords: rostral ventrolateral; subregionally specific; form; ventrolateral medulla ... See more keywords