Pharmacokinetic Interaction Between Telmisartan and Rosuvastatin/Ezetimibe After Multiple Oral Administration in Healthy Subjects
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DOI: 10.1007/s12325-020-01592-8
Abstract: Telmisartan, rosuvastatin and ezetimibe are commonly recommended as combination therapies. However, the pharmacokinetic (PK) interaction among these therapeutic drugs has not been clearly reported. The objective of this study was to investigate possible interactions between… read more here.
Keywords: pharmacokinetic interaction; rosuvastatin ezetimibe; telmisartan rosuvastatin; rosuvastatin ... See more keywords
Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia
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DOI: 10.1007/s40256-020-00421-1
Abstract: Rosuvastatin/ezetimibe combines two lipid-lowering agents: rosuvastatin, an HMG-CoA reductase inhibitor (i.e. statin) with particularly strong inhibitory effects on hepatic cholesterol synthesis, and ezetimibe, which inhibits the intestinal absorption of cholesterol. A fixed-dose combination (FDC) of… read more here.
Keywords: rosuvastatin ezetimibe; rosuvastatin; hypercholesterolemia; cholesterol ... See more keywords
Comparison of Pharmacokinetics and Safety of a Fixed-dose Combination of Rosuvastatin and Ezetimibe Versus Separate Tablets in Healthy Subjects.
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DOI: 10.1016/j.clinthera.2017.07.038
Abstract: PURPOSE Rosuvastatin and ezetimibe are concomitantly used for dyslipidemia treatment. Compared with separate tablets, fixed-dose combination (FDC) tablets of rosuvastatin/ezetimibe could increase patient compliance. The aim of this study was to compare the pharmacokinetic (PK)… read more here.
Keywords: rosuvastatin ezetimibe; dose combination; rosuvastatin; study ... See more keywords
Effects of rosuvastatin/ezetimibe on senescence of CD8+ T-cell in type 2 diabetic patients with hypercholesterolemia: A study protocol
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DOI: 10.1097/md.0000000000031691
Abstract: Background: A decade ago, systemic inflammation became widely recognized as an etiology of type 2 diabetes mellitus (T2DM) and complications thereof. Senescent CD8 + T cells of T2DM patients exhibit increased secretion of pro-inflammatory cytokines and enhanced… read more here.
Keywords: cd8 cell; senescence; type; rosuvastatin ezetimibe ... See more keywords
Pharmacokinetic and pharmacodynamic interaction between ezetimibe and rosuvastatin in healthy male subjects
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DOI: 10.2147/dddt.s146863
Abstract: Background and objective Rosuvastatin and ezetimibe are commonly applied in lipid-lowering pharmacotherapy. However, the pharmacokinetic (PK) interaction was not clear by the coadministration of rosuvastatin and ezetimibe. This study investigated the pharmacodynamic (PD) and PK… read more here.
Keywords: healthy male; rosuvastatin ezetimibe; ezetimibe; male subjects ... See more keywords