Articles with "rotamerization" as a keyword



A Chalcone-Based Potential Therapeutic Small Molecule That Binds to Subdomain IIA in HSA Precisely Controls the Rotamerization of Trp-214

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Published in 2018 at "ACS Omega"

DOI: 10.1021/acsomega.8b01079

Abstract: The principal intent of this work is to explore whether the site-specific binding of a newly synthesized quinoline-appended anthracenyl chalcone, (E)-3-(anthracen-10-yl)-1-(6,8-dibromo-2-methylquinolin-3-yl)prop-2-en-1-one (ADMQ), with an extracellular protein of the human circulatory system, human serum albumin (HSA),… read more here.

Keywords: hsa; trp 214; trp; subdomain iia ... See more keywords