CRISPR/Cas9 screens identify key host factors that enhance rotavirus reverse genetics efficacy and vaccine production
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DOI: 10.1038/s41541-024-01007-7
Abstract: Rotaviruses pose a significant threat to young children. To identify novel pro- and anti-rotavirus host factors, we performed genome-wide CRISPR/Cas9 screens using rhesus rotavirus and African green monkey cells. Genetic deletion of either SERPINB1 or… read more here.
Keywords: host factors; genetics; rotavirus reverse; reverse genetics ... See more keywords