Articles with "rotavirus vaccines" as a keyword



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Polio endgame: Lessons for the global rotavirus vaccination program.

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Published in 2019 at "Vaccine"

DOI: 10.1016/j.vaccine.2019.04.023

Abstract: Poliovirus and rotavirus share notable similarities. Although rotavirus is not amenable to eradication because of animal reservoirs, live, attenuated oral vaccines have been the bedrock of both prevention and control programs, providing intestinal and humoral… read more here.

Keywords: eradication; polio; rotavirus vaccines; parenteral rotavirus ... See more keywords
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Current Update on Rotavirus in-Silico Multiepitope Vaccine Design

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c07213

Abstract: Rotavirus gastroenteritis is one of the leading causes of pediatric morbidity and mortality worldwide in infants and under-five populations. The World Health Organization (WHO) recommended global incorporation of the rotavirus vaccine in national immunization programs… read more here.

Keywords: development; rotavirus; design; silico multiepitope ... See more keywords
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Impact of rotavirus vaccines in low and middle-income countries

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Published in 2017 at "Current Opinion in Infectious Diseases"

DOI: 10.1097/qco.0000000000000397

Abstract: Purpose of review Rotavirus vaccines are playing a pivotal role in improving lives of infants and young children in low and middle-income countries (LMICs). Many of these countries have adopted the vaccine into their routine… read more here.

Keywords: low middle; middle income; rotavirus vaccines; impact rotavirus ... See more keywords
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Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade

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Published in 2019 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.aat5025

Abstract: Rotavirus vaccines have oncolytic properties and can overcome resistance to anti–PD-(L)1/CTLA-4 via RIG-I activation upon intratumoral administration. Repurposing a pediatric vaccine Attenuated virus vaccines such as those used to protect against influenza or chickenpox have… read more here.

Keywords: immune checkpoint; rotavirus; rotavirus vaccines; overcome resistance ... See more keywords
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Kawasaki Disease Following the 13-valent Pneumococcal Conjugate Vaccine and Rotavirus Vaccines.

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Published in 2022 at "Pediatrics"

DOI: 10.1542/peds.2022-058789

Abstract: BACKGROUND Temporal associations between Kawasaki disease (KD) and childhood vaccines have been reported. Limited data on KD following 13-valent pneumococcal conjugate (PCV13) and rotavirus vaccines are available. METHODS We conducted a self-controlled risk interval study… read more here.

Keywords: kawasaki disease; pcv13 rotavirus; risk; following valent ... See more keywords
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Does Anybody Want an Injectable Rotavirus Vaccine, and Why? Understanding the Public Health Value Proposition of Next-Generation Rotavirus Vaccines

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Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10020149

Abstract: Routine infant immunization with live, oral rotavirus vaccines (LORVs) has had a major impact on severe gastroenteritis disease. Nevertheless, in high morbidity and mortality settings rotavirus remains an important cause of disease, partly attributable to… read more here.

Keywords: health; generation rotavirus; rotavirus; next generation ... See more keywords
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Establishment of Sandwich ELISA for Quality Control in Rotavirus Vaccine Production

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Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10020243

Abstract: Non-replicating rotavirus vaccines are alternative strategies that may improve the protective efficacy of rotavirus vaccines in low- and middle-income countries. The truncated spike protein VP4 (aa26-476, VP4*)was a candidate antigen for the development of recombinant… read more here.

Keywords: quality control; development; vp4; rotavirus ... See more keywords
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Understanding Rotavirus Vaccine Efficacy and Effectiveness in Countries with High Child Mortality

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Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10030346

Abstract: Rotavirus claims thousands of lives of children globally every year with a disproportionately high burden in low- and lower-middle income countries where access to health care is limited. Oral, live-attenuated rotavirus vaccines have been evaluated… read more here.

Keywords: vaccine efficacy; rotavirus; mortality; efficacy effectiveness ... See more keywords
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Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines

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Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10030418

Abstract: Following the introduction of live-attenuated rotavirus vaccines in many countries, a notable reduction in deaths and hospitalisations associated with diarrhoea in children read more here.

Keywords: rotavirus vaccines; target effects; rotavirus; live attenuated ... See more keywords