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Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.04.023
Abstract: Poliovirus and rotavirus share notable similarities. Although rotavirus is not amenable to eradication because of animal reservoirs, live, attenuated oral vaccines have been the bedrock of both prevention and control programs, providing intestinal and humoral…
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Keywords:
eradication;
polio;
rotavirus vaccines;
parenteral rotavirus ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c07213
Abstract: Rotavirus gastroenteritis is one of the leading causes of pediatric morbidity and mortality worldwide in infants and under-five populations. The World Health Organization (WHO) recommended global incorporation of the rotavirus vaccine in national immunization programs…
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Keywords:
development;
rotavirus;
design;
silico multiepitope ... See more keywords
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Published in 2017 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000397
Abstract: Purpose of review Rotavirus vaccines are playing a pivotal role in improving lives of infants and young children in low and middle-income countries (LMICs). Many of these countries have adopted the vaccine into their routine…
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Keywords:
low middle;
middle income;
rotavirus vaccines;
impact rotavirus ... See more keywords
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Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aat5025
Abstract: Rotavirus vaccines have oncolytic properties and can overcome resistance to anti–PD-(L)1/CTLA-4 via RIG-I activation upon intratumoral administration. Repurposing a pediatric vaccine Attenuated virus vaccines such as those used to protect against influenza or chickenpox have…
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Keywords:
immune checkpoint;
rotavirus;
rotavirus vaccines;
overcome resistance ... See more keywords
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Published in 2022 at "Pediatrics"
DOI: 10.1542/peds.2022-058789
Abstract: BACKGROUND Temporal associations between Kawasaki disease (KD) and childhood vaccines have been reported. Limited data on KD following 13-valent pneumococcal conjugate (PCV13) and rotavirus vaccines are available. METHODS We conducted a self-controlled risk interval study…
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Keywords:
kawasaki disease;
pcv13 rotavirus;
risk;
following valent ... See more keywords
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Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10020149
Abstract: Routine infant immunization with live, oral rotavirus vaccines (LORVs) has had a major impact on severe gastroenteritis disease. Nevertheless, in high morbidity and mortality settings rotavirus remains an important cause of disease, partly attributable to…
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Keywords:
health;
generation rotavirus;
rotavirus;
next generation ... See more keywords
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Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10020243
Abstract: Non-replicating rotavirus vaccines are alternative strategies that may improve the protective efficacy of rotavirus vaccines in low- and middle-income countries. The truncated spike protein VP4 (aa26-476, VP4*)was a candidate antigen for the development of recombinant…
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Keywords:
quality control;
development;
vp4;
rotavirus ... See more keywords
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Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10030346
Abstract: Rotavirus claims thousands of lives of children globally every year with a disproportionately high burden in low- and lower-middle income countries where access to health care is limited. Oral, live-attenuated rotavirus vaccines have been evaluated…
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Keywords:
vaccine efficacy;
rotavirus;
mortality;
efficacy effectiveness ... See more keywords
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Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10030418
Abstract: Following the introduction of live-attenuated rotavirus vaccines in many countries, a notable reduction in deaths and hospitalisations associated with diarrhoea in children
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Keywords:
rotavirus vaccines;
target effects;
rotavirus;
live attenuated ... See more keywords