Efficient Route for Construction of Fluorinated Isoxazolines through Base‐Mediated Fluorinated Amino Acid Derivatives
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DOI: 10.1002/ejoc.202500653
Abstract: Isoxazolines have attracted widespread attention for the development of anticancer, antiviral, and anti‐inflammatory drugs due to their unique electronic properties and conformational rigidity. However, the application of fluorinated isoxazolines in the development of innovative drugs… read more here.
Keywords: isoxazolines base; efficient route; route construction; amino ... See more keywords
Efficient route for the construction of polycyclic systems from bioderived HMF
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DOI: 10.1039/c7gc02211e
Abstract: The first synthesis of tricyclic compounds from biobased 5-hydroxymethylfurfural (HMF) is described. The Diels–Alder reaction was used to implement the transition from HMF to a non-planar framework, which possessed structural cores of naturally occurring biologically… read more here.
Keywords: systems bioderived; polycyclic systems; route construction; efficient route ... See more keywords