RP1, a RAGE antagonist peptide, can improve memory impairment and reduce Aβ plaque load in the APP/PS1 mouse model of Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108304
Abstract: Amyloid-β (Aβ) accumulation is a pathological hallmark of Alzheimer's disease (AD). The receptor for advanced glycation end products (RAGE) is involved in the production and accumulation of Aβ. RP1, a peptide antagonist of RAGE, was… read more here.
Keywords: alzheimer disease; rp1; memory impairment; rage ... See more keywords
Peptide-driven control of somersaulting in Hydra vulgaris
Sign Up to like & getrecommendations! Published in 2023 at "Current Biology"
DOI: 10.2139/ssrn.4309092
Abstract: The cnidarian Hydra vulgaris has a simple nervous system with a few hundred neurons in distributed networks. Yet Hydra can perform somersaults, a complex acrobatic locomotion. To understand the neural mechanisms of somersaulting we used… read more here.
Keywords: rp1; rp1 neurons; control somersaulting; peptide driven ... See more keywords
Analysis of Extreme Phenotype Bulk Copy Number Variation (XP-CNV) Identified the Association of rp1 with Resistance to Goss's Wilt of Maize
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2018.00110
Abstract: Goss's wilt (GW) of maize is caused by the Gram-positive bacterium Clavibacter michiganensis subsp. nebraskensis (Cmn) and has spread in recent years throughout the Great Plains, posing a threat to production. The genetic basis of… read more here.
Keywords: copy number; rp1; goss wilt; resistance ... See more keywords