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RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

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1 Published in 2017 at "Molecular Cell"

DOI: 10.1016/j.molcel.2017.04.021

Abstract: Summary Defects in the repair of DNA interstrand crosslinks (ICLs) are associated with the genome instability syndrome Fanconi anemia (FA). Here we report that cells with mutations in RFWD3, an E3 ubiquitin ligase that interacts… read more here.

Keywords: interstrand; rfwd3; rpa mediated; human health ... See more keywords