Articles with "rpa rad51" as a keyword



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HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51

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Published in 2021 at "Nature"

DOI: 10.1038/s41586-021-04261-0

Abstract: DNA double-stranded breaks (DSBs) are deleterious lesions, and their incorrect repair can drive cancer development 1 . HELQ is a superfamily 2 helicase with 3′ to 5′ polarity, and its disruption in mice confers germ… read more here.

Keywords: dna; rad51; strand annealing; rpa rad51 ... See more keywords