Ribosomal protein L5 (RPL5)/ E2F transcription factor 1 (E2F1) signaling suppresses breast cancer progression via regulating endoplasmic reticulum stress and autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2052672
Abstract: ABSTRACT Endoplasmic reticulum stress (ERS) is associated with breast cancer progression. However, the potential role of ribosomal protein L5 (RPL5) on ERS in breast cancer remains unclear. This study aimed to determine the role of… read more here.
Keywords: endoplasmic reticulum; reticulum stress; rpl5; breast cancer ... See more keywords
A new murine Rpl5(uL18) mutation provides a unique model of variably penetrant Diamond Blackfan Anemia.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2021004658
Abstract: Ribosome dysfunction is implicated in multiple abnormal developmental and disease states in humans. Heterozygous germline mutations in genes encoding ribosomal proteins (RPs) are found in the majority of individuals with Diamond Blackfan anemia (DBA) while… read more here.
Keywords: new murine; rpl5; blackfan anemia; diamond blackfan ... See more keywords
The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.777121
Abstract: Ribosomal biogenesis is a fundamental process necessary for cell growth and division. Ribosomal protein L5 (Rpl5) is part of the large ribosomal subunit. Mutations in this protein have been associated with the congenital disease Diamond… read more here.
Keywords: loss function; rpl5; tissue; rpl5 knockdown ... See more keywords
Reliable reference genes for gene expression analyses under the hypomagnetic field in a migratory insect
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.954228
Abstract: Manipulating the hypomagnetic field (HMF), which is the absence or significant weakening ( read more here.
Keywords: rpl5; expression; physiology; gene expression ... See more keywords