Expression analysis of human solute carrier (SLC) family transporters in nasal mucosa and RPMI 2650 cells
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.07.040
Abstract: ABSTRACT With nearly 400 members, the solute‐linked carrier (SLC) superfamily is one of the most important gene classes concerning the disposition of drugs and the transport of physiological substrates in the human body. The mapping… read more here.
Keywords: 2650 cells; nasal mucosa; expression; rpmi 2650 ... See more keywords
Pharmacological Characterization of the RPMI 2650 Model as a Relevant Tool for Assessing the Permeability of Intranasal Drugs.
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DOI: 10.1021/acs.molpharmaceut.8b00087
Abstract: The RPMI 2650 cell line has been described as a potent model of the human nasal mucosa. Nevertheless, pharmacological data are still insufficient, and the role of drug efflux transporters has not been fully elucidated.… read more here.
Keywords: pharmacological characterization; model; rpmi 2650; tool assessing ... See more keywords
Applicability of RPMI 2650 and Calu-3 Cell Models for Evaluation of Nasal Formulations
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DOI: 10.3390/pharmaceutics14020369
Abstract: The RPMI 2650 and Calu-3 cell lines have been previously evaluated as models of the nasal and airway epithelial barrier, and they have demonstrated the potential to be used in drug permeation studies. However, limited… read more here.
Keywords: cell; 2650 calu; cell models; rpmi 2650 ... See more keywords