Synthesis, structure, properties, and cytotoxicity of a (quinoline)RuCp+ complex.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt03484k
Abstract: A rare example of a structurally characterized metal quinoline complex was prepared using a non-covalent quinoline-based proteasome inhibitor (Quin1), and a related complex bearing an inactive quinoline ligand (Quin2) was also synthesized. The quinolines are… read more here.
Keywords: rpmi 8226; cytotoxicity; dmso; pf6 ... See more keywords
Cytotoxic Effects of the Schweinfurthin Analog 5′-Methylschweinfurthin G in Malignant Plasma Cells
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DOI: 10.1159/000525299
Abstract: Introduction: Multiple myeloma (MM) is a B plasma cell malignancy currently incurable, and novel therapeutics are needed. Evidences regarding the effect of natural compound schweinfurthins suggest that hematological cancers showed growth inhibitory effects to this… read more here.
Keywords: cell; rpmi 8226; analog methylschweinfurthin; cytotoxic effects ... See more keywords
Expression and Importance of TMED2 in Multiple Myeloma Cells
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DOI: 10.2147/cmar.s278570
Abstract: Objective TMED2 is a member of the transmembrane emp24 domain (Tmed)/p24 protein family, which is significantly upregulated in breast cancer, ovarian cancer and other tumour tissues. The purpose of this study was to investigate the… read more here.
Keywords: expression; rpmi 8226; cell; tmed2 ... See more keywords
Force-Regulated Calcium Signaling of Lymphoid Cell RPMI 8226 Mediated by Integrin α4β7/MAdCAM-1 in Flow
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DOI: 10.3390/biom13040587
Abstract: MAdCAM-1 binds to integrin α4β7, which mediates the rolling and arrest of circulating lymphocytes upon the vascular endothelia during lymphocytic homing. The calcium response by adhered lymphocytes is a critical event for lymphocyte activation and… read more here.
Keywords: rpmi 8226; calcium; calcium signaling; integrin ... See more keywords
Involvement of the TGFβ1/Smad2/MMP3 signaling pathway in SB431542-induced inhibition of cell invasion in multiple myeloma RPMI 8226 cells
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DOI: 10.3892/ol.2017.6263
Abstract: Multiple myeloma (MM) is a malignancy characterized by plasma cell hyperplasia. The majority of patients with MM suffer from mortality due to tumor recurrence and metastasis, which has become an emerging clinical problem. Transforming growth… read more here.
Keywords: 8226 cells; rpmi 8226; smad2 mmp3; tgf ... See more keywords