The antiretroviral agents azidothymidine, stavudine, and didanosine have the identical mutational fingerprint in the rpoB region of Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22507
Abstract: We looked at the mutational fingerprints of three antiretroviral (anti‐HIV) agents, azidothymidine (AZT), stavudine (STAV), and didanosine (DIDA) in the rpoB system of Escherichia coli and compared them with each other and with the fingerprints… read more here.
Keywords: antiretroviral agents; escherichia coli; rpob; fingerprint ... See more keywords
First Report of Bacterial Wilt Caused by Enterobacter mori of Strawberry in Beijing, China.
Sign Up to like & getrecommendations! Published in 2022 at "Plant disease"
DOI: 10.1094/pdis-08-22-1895-pdn
Abstract: Strawberry (Fragaria × ananassa) is an economically important crop in China, and a crucial part of urban agriculture in Beijing. In November 2020, wilt symptoms were observed in strawberry seedlings in several greenhouses in the… read more here.
Keywords: infb; rpob; infb rpob; gyrb infb ... See more keywords
Environmental Dependence of Competitive Fitness in Rifampin-Resistant rpoB Mutants of Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02422-21
Abstract: Microbial resistance to antibiotics is a growing threat to public health across the world. Historically, resistance to antibiotics has been associated with reduced fitness. ABSTRACT RNA polymerase (RNAP) is a highly conserved macromolecular machine that… read more here.
Keywords: bacillus subtilis; rpob; resistance; rifampin ... See more keywords
Low-Level Rifampin Resistance and rpoB Mutations in Mycobacterium tuberculosis: an Analysis of Whole-Genome Sequencing and Drug Susceptibility Test Data in New York
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01885-20
Abstract: Rapid and reliable detection of rifampin (RIF) resistance is critical for the diagnosis and treatment of drug-resistant and multidrug-resistant (MDR) tuberculosis. Discordant RIF phenotype/genotype susceptibility results remain a challenge due to the presence of rpoB… read more here.
Keywords: rpob mutations; rif resistance; level; resistance ... See more keywords
Genetic Heterogeneity of Alicyclobacillus Strains Revealed by RFLP Analysis of vdc Region and rpoB Gene
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/9608756
Abstract: PCR-RFLP targeting of the 16S rDNA and rpoB genes, as well as the vdc region, was applied to identify and differentiate between the spoilage and non-spoilage Alicyclobacillus species. Eight reference strains and 75 strains isolated… read more here.
Keywords: vdc region; analysis; heterogeneity; gene ... See more keywords
Evaluation of the performance of an in-house duplex PCR assay targeting the IS6110 and rpoB genes for tuberculosis diagnosis in Cameroon
Sign Up to like & getrecommendations! Published in 2020 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-020-05523-4
Abstract: Background Tuberculosis (TB) remains a major public health concern in many low-income countries accounting for approximately two-thirds of deaths in people living with human immunodeficiency virus (HIV) infection. With prompt, accurate and appropriate treatment, almost… read more here.
Keywords: microscopy; pcr; tuberculosis; duplex pcr ... See more keywords
Genotypic distribution of multidrug-resistant and extensively drug-resistant tuberculosis in northern Thailand
Sign Up to like & getrecommendations! Published in 2017 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s130203
Abstract: Background Multidrug/extensively drug-resistant tuberculosis (M/XDR-TB) is a major public health problem, and early detection is important for preventing its spread. This study aimed to demonstrate the distribution of genetic site mutation associated with drug resistance… read more here.
Keywords: drug resistance; mutation; drug; rpob ... See more keywords
rpoB Mutations are Associated with Variable Levels of Rifampin and Rifabutin Resistance in Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s386863
Abstract: Objective To assess the relationship between the variant rpoB mutations and the degree of rifampin (RIF)/rifabutin (RFB) resistance in Mycobacterium tuberculosis (M. tuberculosis). Methods We analyzed the whole rpoB gene in 177 M. tuberculosis clinical… read more here.
Keywords: tuberculosis; rpob; level; resistance ... See more keywords
Mutation of rpoB Shifts the Nutrient Threshold Triggering Myxococcus Multicellular Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.817080
Abstract: The ability to perceive and respond to environmental change is essential to all organisms. In response to nutrient depletion, cells of the soil-dwelling δ-proteobacterium Myxococcus xanthus undergo collective morphogenesis into multicellular fruiting bodies and transform… read more here.
Keywords: development; myxococcus; rpob; multicellular ... See more keywords