An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity
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DOI: 10.1172/jci.insight.161810
Abstract: Diamond-Blackfan anemia (DBA) is a genetic blood disease caused by heterozygous loss-of-function mutations in ribosomal protein (RP) genes, most commonly RPS19. The signature feature of DBA is hypoplastic anemia occurring in infants, although some older… read more here.
Keywords: blackfan anemia; diamond blackfan; hematopoietic stem; anemia ... See more keywords