Bacterial Rps3 counters oxidative and UV stress by recognizing and processing AP-sites on mRNA via a novel mechanism
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae1130
Abstract: Abstract Lesions and stable secondary structures in mRNA severely impact the translation efficiency, causing ribosome stalling and collisions. Prokaryotic ribosomal proteins Rps3, Rps4 and Rps5, located in the mRNA entry tunnel, form the mRNA helicase… read more here.
Keywords: oxidative stress; mrna via; mechanism; via novel ... See more keywords
A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer"
DOI: 10.1186/s12943-021-01404-9
Abstract: Background Constitutive activation of nuclear factor-κB (NF-κB) signaling plays a key role in the development and progression of colorectal carcinoma (CRC). However, the underlying mechanisms of excessive activation of NF-κB signaling remain largely unknown. Methods… read more here.
Keywords: colorectal carcinoma; ubiquitin dependent; rps3; crc ... See more keywords
RPS3-induced antiviral cytokines inhibit the proliferation of classical swine fever virus.
Sign Up to like & getrecommendations! Published in 2022 at "Acta virologica"
DOI: 10.4149/av_2022_107
Abstract: Classical swine fever virus (CSFV) infection results in serious economic losses to the pig industry. This positive-sense RNA virus hijacks cell host proteins for its own replication. Although previous studies have shown that RPS3, a 40S… read more here.
Keywords: rps3; classical swine; fever virus; swine fever ... See more keywords