Role of RPTPβ/ζ in neuroinflammation and microglia-neuron communication
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-76415-5
Abstract: Pleiotrophin (PTN) is a cytokine that is upregulated in different neuroinflammatory disorders. Using mice with transgenic PTN overexpression in the brain (Ptn-Tg), we have found a positive correlation between iNos and Tnfα mRNA and Ptn… read more here.
Keywords: ptn; neuron communication; role; rptp ... See more keywords
The role of RPTPz in neuronal intracellular pH homeostasis and in crosstalk to adjacent astrocytes
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731322
Abstract: Receptor protein tyrosine phosphatase ζ (RPTPζ) is a transmembrane protein almost exclusively expressed in the CNS regulates cells adhesion and signaling during development. RPTPζ ‘s close homolog RPTPγ, senses extracellular CO₂/HCO₃⁻ and modulates acid-base transport… read more here.
Keywords: rptp neurons; phi; rac; physiology ... See more keywords