HGG-20. DIAGNOSTIC AND BIOLOGICAL ROLE OF METHYLATION PATTERNS IN REPLICATION REPAIR DEFICIENT HIGH GRADE GLIOMAS
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DOI: 10.1093/neuonc/noaa222.307
Abstract: Abstract Replication repair deficiency (RRD) is an important driving mechanism of pediatric high grade glioma (pHGG) occurring predominantly in the context of germline mutations in RRD-associated genes. Although pHGG present specific patterns of DNA methylation… read more here.
Keywords: methylation; replication repair; methylation patterns; rrd phgg ... See more keywords