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   Articles with "rrm" as a keyword



Quality of life after risk reducing mastectomy in a Portuguese cohort of BRCA pathogenic/likely pathogenic variant carriers

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recommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-025-06231-9

Abstract: Women with pathogenic/likely pathogenic (P/LP) variants in BRCA1/2 genes have an increased lifetime risk of breast and ovarian cancer. Cancer risk management options include intensive breast surveillance (IBS) and risk reducing mastectomy (RRM). This study… read more here.

Keywords: cancer; breast; history; quality life ... See more keywords

Throughput, capacity and latency analysis of P-NOMA RRM schemes in 5G URLLC

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recommendations! Published in 2021 at "Multimedia Tools and Applications"

DOI: 10.1007/s11042-021-11086-6

Abstract: 5G is expected to cover a wide range of potential use cases due to its flexible and configurable physical layer waveform. One of the use cases proposed is the application of 5G on Ultra-Reliable Low… read more here.

Keywords: rrm; throughput capacity; noma; capacity latency ... See more keywords

Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

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recommendations! Published in 2017 at "Journal of the American Society for Mass Spectrometry"

DOI: 10.1007/s13361-017-1830-9

Abstract: AbstractThe human GW182 protein plays an essential role in micro(mi)RNA-dependent gene silencing. miRNA silencing is mediated, in part, by a GW182 C-terminal region called the silencing domain, which interacts with the poly(A) binding protein and… read more here.

Keywords: rrm; silencing domain; domain; mass spectrometry ... See more keywords

ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.11.088

Abstract: ATP is the universal energy currency for all cells but has cellular concentrations of 2-12 mM, much higher than required for its classic functions. RNA-recognition motif (RRM) constitutes one of the most abundant domains in eukaryotes… read more here.

Keywords: tdp rrm; fibrillation; als associated; rrm ... See more keywords

Current knowledge of risk reducing mastectomy: Indications, techniques, results, benefits, harms.

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recommendations! Published in 2019 at "Breast"

DOI: 10.1016/j.breast.2019.03.011

Abstract: The last twenty years have seen a complete change in society's attitude to the strategy of risk reduction of breast cancer in high-risk individuals by means of proactive mastectomy. Once termed 'prophylactic mastectomy', risk reducing… read more here.

Keywords: risk reducing; risk; breast cancer; rrm ... See more keywords

Proteome-Level Analysis Indicates Global Mechanisms for Post-Translational Regulation of RRM Domains.

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recommendations! Published in 2018 at "Journal of molecular biology"

DOI: 10.1016/j.jmb.2017.11.001

Abstract: RRM, or RNA-recognition motif, domains are the largest class of single-stranded RNA binding domains in the human proteome and play important roles in RNA processing, splicing, export, stability, packaging, and degradation. Using a current database… read more here.

Keywords: rrm; post translational; rrm domain; rrm domains ... See more keywords

Human CSTF2 RNA Recognition Motif Domain Binds to a U-Rich RNA Sequence through a Multistep Binding Process

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recommendations! Published in 2024 at "Biochemistry"

DOI: 10.1021/acs.biochem.4c00408

Abstract: The RNA recognition motif (RRM) is a conserved and ubiquitous RNA-binding domain that plays essential roles in mRNA splicing, polyadenylation, transport, and stability. RRM domains exhibit remarkable diversity in binding partners, interacting with various sequences… read more here.

Keywords: cstf2; rna; rich rna; rrm ... See more keywords

Optimizing shared decision-making for risk-reducing mastectomy in women with Li–Fraumeni syndrome using patient-reported outcome measures

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-89068-z

Abstract: Decisions regarding risk-reducing mastectomy (RRM) in women with Li–Fraumeni Syndrome (LFS) are challenged by unclear survival benefits and potential quality of life (QOL) impacts. We evaluated QOL in LFS women and identified factors associated with… read more here.

Keywords: fraumeni syndrome; risk reducing; risk; reducing mastectomy ... See more keywords

Spontaneous binding of single-stranded RNAs to RRM proteins visualized by unbiased atomistic simulations with a rescaled RNA force field

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recommendations! Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac1106

Abstract: Recognition of single-stranded RNA (ssRNA) by RNA recognition motif (RRM) domains is an important class of protein-RNA interactions. Many such complexes were characterized using NMR and/or X-ray crystallography techniques, revealing ensemble-averaged pictures of the bound… read more here.

Keywords: single stranded; rrm; rna; force field ... See more keywords

Advanced NOMA-Based RRM Schemes for Broadcasting in 5G mmWave Frequency Bands

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recommendations! Published in 2022 at "IEEE Transactions on Broadcasting"

DOI: 10.1109/tbc.2021.3128049

Abstract: A relevant solution for the high demand for new multimedia applications and services is millimeter wave (mmWave) frequency band in 5G. However, in order to face the technological challenges of the present and those that… read more here.

Keywords: rrm; frequency; noma based; frequency bands ... See more keywords

Artificial Intelligence Aided Low Complexity RRM Algorithms for 5G-MBS

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recommendations! Published in 2024 at "IEEE Transactions on Broadcasting"

DOI: 10.1109/tbc.2023.3311337

Abstract: For the upcoming 5G-Advanced, the multicast/broadcast services (5G-MBS) capability is one of the most appealing use cases. The effective integration of point-to-multipoint communication will address the ever-growing traffic demands, disruptive multimedia services, massive connectivity, and… read more here.

Keywords: access technique; artificial intelligence; access; complexity ... See more keywords