RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis
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DOI: 10.1038/s41467-020-19658-0
Abstract: Primary microcephaly (MCPH) is characterized by reduced brain size and intellectual disability. The exact pathophysiological mechanism underlying MCPH remains to be elucidated, but dysfunction of neuronal progenitors in the developing neocortex plays a major role.… read more here.
Keywords: primary microcephaly; neurogenesis; dysfunction; rrp7a ... See more keywords