Effect of risk-reducing salpingo-oophorectomy on quality of life in Korean BRCA mutation carriers.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of surgery"
DOI: 10.1016/j.asjsur.2021.01.007
Abstract: BACKGROUND This study aimed to compare the quality of life (QOL), psychosocial status, sexual function, and menopausal symptoms between the risk-reducing salpingo-oophorectomy (RRSO) and non-RRSO groups comprising BRCA mutation carriers and to evaluate the effect… read more here.
Keywords: mutation carriers; rrso group; brca mutation; rrso ... See more keywords
Safety of hormone replacement therapy following risk-reducing salpingo-oophorectomy: systematic review of literature and guidelines
Sign Up to like & getrecommendations! Published in 2019 at "Climacteric"
DOI: 10.1080/13697137.2019.1582622
Abstract: Abstract Background: Women at high risk to develop ovarian cancer opt for risk-reducing salpingo-oophorectomy (RRSO) to reduce the risk by 80–96%. RRSO leads to a direct onset of menopause in premenopausal women. Hormone replacement therapy… read more here.
Keywords: risk; risk reducing; salpingo oophorectomy; rrso ... See more keywords
Long-term tumour dormancy in a BRCA1 heterozygote
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2021-108269
Abstract: Ovarian highgrade serous carcinoma (HGSC) is thought to mainly arise from the Fallopian tubes from a precursor lesion known as serous tubal intraepithelial carcinoma (STIC). 2 Germline pathogenic variants (GPVs) in BRCA1/2 are the most… read more here.
Keywords: brca1; hgsc; rrso; tumour ... See more keywords
Development of Peritoneal Carcinoma in women diagnosed with Serous Tubal Intraepithelial Carcinoma (STIC) following Risk-Reducing Salpingo-Oophorectomy (RRSO)
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ovarian Research"
DOI: 10.1186/s13048-019-0525-1
Abstract: IntroductionThe management of Serous Tubal Intraepithelial Carcinoma (STIC) found at the time of Risk-Reducing Salpingo-Oophorectomy (RRSO) remains unclear. We set out to analyse the incidence of peritoneal carcinomas developed after prophylactic surgery and to formulate… read more here.
Keywords: risk; carcinoma; tubal intraepithelial; rrso ... See more keywords
Pathologic findings at risk-reducing salpingo-oophorectomy in germline BRCA mutation carriers: Optimal age of bilateral RRSO.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e13046
Abstract: e13046Background: Most BRCA1/2 carriers do not undergo risk-reducing salpingo-oophorectomy (RRSO) by the recommended age of 40. Methods: We retrospectively reviewed breast cancer patients identified as BRCA mutation carriers who underwent RRSO at Asan Medical Center,… read more here.
Keywords: risk reducing; salpingo oophorectomy; age; rrso ... See more keywords
High-Grade Serous Carcinoma at Risk-Reducing Salpingo-Oophorectomy in Asymptomatic Carriers of BRCA1/2 Pathogenic Variants: Prevalence and Clinical Factors
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.22.01237
Abstract: PURPOSE To investigate the prevalence of and clinical factors associated with high-grade serous carcinoma (HGSC) at risk-reducing salpingo-oophorectomy (RRSO) in asymptomatic BRCA1/2-pathogenic variant (PV) carriers. PATIENTS AND METHODS We included BRCA1/2-PV carriers who underwent RRSO… read more here.
Keywords: brca1; clinical factors; high grade; rrso ... See more keywords