Genetic association of TMPRSS2 rs2070788 polymorphism with COVID-19 case fatality rate among Indian populations
Sign Up to like & getrecommendations! Published in 2022 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2022.105206
Abstract: SARS-CoV2, the causative agent for COVID-19, an ongoing pandemic, engages the ACE2 receptor to enter the host cell through S protein priming by a serine protease, TMPRSS2. Variation in the TMPRSS2 gene may account for… read more here.
Keywords: tmprss2; tmprss2 gene; gene; rs2070788 ... See more keywords
Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans
Sign Up to like & getrecommendations! Published in 2021 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2020-0484
Abstract: Abstract For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the importance of population… read more here.
Keywords: rs2070788; cov interactome; human sars; genetics ... See more keywords