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   Articles with "rsad2" as a keyword



Interferon-α regulates abnormally increased expression of RSAD2 in Th17 and Tfh cells in systemic lupus erythematosus patients.

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recommendations! Published in 2023 at "European journal of immunology"

DOI: 10.1002/eji.202350420

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that often involves abnormal activation of regulatory interferon genes and regulation of B cells by CD4+ T cells. RSAD2 is a viral suppressor protein regulated by… read more here.

Keywords: tfh cells; th17; expression; systemic lupus ... See more keywords

Rsad2 mediates Bisphenol A‐induced actin cytoskeletal disruption in mouse spermatocytes

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recommendations! Published in 2024 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4649

Abstract: Bisphenol A (BPA) is widely exposed in populations worldwide and has negative effects on spermatogenesis both in animals and humans. The homeostasis of the actin cytoskeleton in the spermatogenic epithelium is crucial for spermatogenesis. Actin… read more here.

Keywords: bpa induced; bpa; induced actin; actin cytoskeletal ... See more keywords

Knockdown of RSAD2 attenuates B cell hyperactivity in patients with primary Sjögren's syndrome (pSS) via suppressing NF-κb signaling pathway.

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recommendations! Published in 2021 at "Molecular and cellular biochemistry"

DOI: 10.1007/s11010-021-04070-z

Abstract: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that is mainly characterized as abnormal activation of B cells. It is reported that radical s-adenosyl methionine domain-containing 2 (RSAD2) is overexpressed in CD19+ B cells… read more here.

Keywords: gren syndrome; rsad2; pss; knockdown rsad2 ... See more keywords

RSAD2 is abundant in atherosclerotic plaques and promotes interferon-induced CXCR3-chemokines in human smooth muscle cells

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-58592-9

Abstract: In atherosclerotic lesions, monocyte-derived macrophages are major source of interferon gamma (IFN-γ), a pleotropic cytokine known to regulate the expression of numerous genes, including the antiviral gene RSAD2. While RSAD2 was reported to be expressed… read more here.

Keywords: muscle cells; smooth muscle; rsad2; cxcr3 chemokines ... See more keywords