Interferon-α regulates abnormally increased expression of RSAD2 in Th17 and Tfh cells in systemic lupus erythematosus patients.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202350420
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that often involves abnormal activation of regulatory interferon genes and regulation of B cells by CD4+ T cells. RSAD2 is a viral suppressor protein regulated by… read more here.
Keywords: tfh cells; th17; expression; systemic lupus ... See more keywords
Knockdown of RSAD2 attenuates B cell hyperactivity in patients with primary Sjögren's syndrome (pSS) via suppressing NF-κb signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04070-z
Abstract: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that is mainly characterized as abnormal activation of B cells. It is reported that radical s-adenosyl methionine domain-containing 2 (RSAD2) is overexpressed in CD19+ B cells… read more here.
Keywords: gren syndrome; rsad2; pss; knockdown rsad2 ... See more keywords