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   Articles with "rspo1" as a keyword



Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet‐Induced Adiposity (Adv. Sci. 12/2023)

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recommendations! Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202207152

Abstract: Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161… read more here.

Keywords: rspo1; induced adiposity; mutation; thermogenesis ... See more keywords

Amphiregulin mediates the hormonal regulation on Rspondin-1 expression in the mammary gland.

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recommendations! Published in 2019 at "Developmental biology"

DOI: 10.1016/j.ydbio.2019.10.006

Abstract: The steroid hormones are instrumental for the growth of mammary epithelial cells. Our previous study indicates that hormones regulate the expression of Rspondin-1 (Rspo1). Yet, the regulatory mechanism remains unknown. In the current study, we… read more here.

Keywords: amphiregulin; rspondin; mammary gland; rspo1 ... See more keywords

Identification and Validation of Immune Implication of R-Spondin 1 and an R-Spondin 1-Related Prognostic Signature in Esophagus Cancer

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recommendations! Published in 2024 at "International Journal of Genomics"

DOI: 10.1155/2024/7974277

Abstract: R-spondin 1 (RSPO1), which encodes a secretory-activating protein, is a promising therapeutic target for various tumors. The aim of this study was to establish a robust RSPO1-related signature specific to esophageal cancer (ESCA). Our comprehensive… read more here.

Keywords: cancer; rspo1; rspo1 expression; signature ... See more keywords

A Novel Identified Long Non-coding RNA, lncRNA MEF2C-AS1, Inhibits Cervical Cancer via Regulation of miR-592/RSPO1

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recommendations! Published in 2021 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2021.687113

Abstract: Purpose: Our purpose was to investigate the effect of lncRNA MEF2C antisense RNA 1 (MEF2C-AS1) on cervical cancer and further explore its underlying molecular mechanisms. Methods: The proliferation, migration and invasion of CC cells were… read more here.

Keywords: rspo1; lncrna mef2c; mef2c as1; mir 592 ... See more keywords