ER stress protein PERK promotes inappropriate innate immune responses and pathogenesis during RSV infection
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0520-322rr
Abstract: The activation of dendritic cells (DC) during respiratory viral infections is central to directing the immune response and the pathologic outcome. In these studies, the effect of RSV infection on development of ER stress responses… read more here.
Keywords: perk; innate; rsv infection; infection ... See more keywords
TRIM22 inhibits respiratory syncytial virus replication by targeting JAK‐STAT1/2 signaling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26436
Abstract: Respiratory syncytial virus (RSV) infection is a major cause of lower respiratory tract disease. Although RSV causes major economic losses every year, effective treatments have not been found so far. Recent studies have shown that… read more here.
Keywords: respiratory syncytial; jak stat1; rsv infection;
Using urine metabolomics to understand the pathogenesis of infant respiratory syncytial virus (RSV) infection and its role in childhood wheezing
Sign Up to like & getrecommendations! Published in 2018 at "Metabolomics"
DOI: 10.1007/s11306-018-1431-z
Abstract: BackgroundRespiratory syncytial virus (RSV) infection in infants causes significant morbidity and is the strongest risk factor associated with asthma. Metabolites, which reflect the interactions between host cell and virus, provide an opportunity to identify the… read more here.
Keywords: virus rsv; syncytial virus; infection; rsv infection ... See more keywords
Neutralization of nerve growth factor (NGF) inhibits the Th2 response and protects against the respiratory syncytial virus (RSV) infection
Sign Up to like & getrecommendations! Published in 2017 at "Immunologic Research"
DOI: 10.1007/s12026-017-8909-z
Abstract: Increasing evidence suggests that respiratory syncytial virus (RSV) infection during the early life is an important risk factor for the development of asthma. RSV infection is associated with neurogenic inflammation in the airways along with… read more here.
Keywords: respiratory syncytial; syncytial virus; rsv; factor ... See more keywords
Defining the Risk and Associated Morbidity and Mortality of Severe Respiratory Syncytial Virus Infection Among Infants with Congenital Heart Disease
Sign Up to like & getrecommendations! Published in 2017 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-016-0142-x
Abstract: IntroductionThe REGAL (RSV Evidence—a Geographical Archive of the Literature) series provide a comprehensive review of the published evidence in the field of respiratory syncytial virus (RSV) in Western countries over the last 20 years. This fourth… read more here.
Keywords: infection; rsv; morbidity mortality; soe ... See more keywords
Fulminant ecchymosis as the initial manifestation of antiphospholipid syndrome (APS) triggered by respiratory syncytial virus (RSV) infection: A case report and review of the literature
Sign Up to like & getrecommendations! Published in 2017 at "IDCases"
DOI: 10.1016/j.idcr.2016.10.013
Abstract: Abstract We present a unique and informative instance of respiratory syncytial virus (RSV) infection associated with antiphospholipid syndrome (APS), and discuss this case in the context of the literature addressing the immunopathogenesis of APS associated… read more here.
Keywords: respiratory syncytial; syncytial virus; case; rsv ... See more keywords
Macrophages produce IL‐33 by activating MAPK signaling pathway during RSV infection
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2017.05.008
Abstract: HighlightsMacrophages are a cellular source of IL‐33 during RSV infection.Macrophages produce IL‐33 via MAPK signaling pathway under RSV infection.JNK may play a critical role in RSV‐induced IL‐33 production in macrophages.NF‐&kgr;B may not participate in IL‐33… read more here.
Keywords: production; infection; signaling pathway; mapk signaling ... See more keywords
Uric acid pathway activation during Respiratory virus infection promotes Th2 immune responses via innate cytokine production and ILC2 accumulation
Sign Up to like & getrecommendations! Published in 2020 at "Mucosal immunology"
DOI: 10.1038/s41385-020-0264-z
Abstract: Respiratory syncytial virus (RSV) infects a majority of infants and can cause severe disease leading to increased risk to develop asthma later in life. In the present studies we detected high levels of uric acid… read more here.
Keywords: uric acid; infection; rsv; acid pathway ... See more keywords
Control of IFN-I responses by the aminopeptidase IRAP in neonatal C57BL/6 alveolar macrophages during RSV infection
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DOI: 10.1038/s41385-021-00402-w
Abstract: Respiratory Syncytial Virus (RSV) is the major cause of lower respiratory tract infection in infants, in whom, the sensing of RSV by innate immune receptors and its regulation are still poorly described. However, the severe… read more here.
Keywords: alveolar macrophages; infection; neonatal c57bl; aminopeptidase irap ... See more keywords
Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo
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DOI: 10.1080/19420862.2018.1433974
Abstract: ABSTRACT Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization and mortality in young children. Protective therapy options are limited. Currently, palivizumab, a monoclonal IgG1 antibody, is the only licensed drug for RSV… read more here.
Keywords: iga; human iga; infection; palivizumab motavizumab ... See more keywords
653: HUMAN METAPNEUMOVIRUS IS MORE SEVERE THAN RSV INFECTION IN HOSPITALIZED CHILDREN
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000626352.89599.09
Abstract: Introduction/Hypothesis: Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are the two most common causes of acute respiratory tract infections in infants and young children. The objective of this study is to compare demographics and… read more here.
Keywords: human metapneumovirus; rsv; children hmpv; infection ... See more keywords