IGF2 drives formation of ileal neuroendocrine tumors in patients and mice.
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DOI: 10.1530/erc-19-0505
Abstract: By the strictest of definitions, a genetic driver of tumorigenesis should fulfill two criteria: it should be altered in a high percentage of patient tumors, and it should also be able to cause the same… read more here.
Keywords: genetic background; neuroendocrine tumors; ileal neuroendocrine; rt2 mice ... See more keywords