Renal involvement in primary Sjogren’s syndrome: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4118-x
Abstract: The objective of the study is to prospectively evaluate the spectrum of clinical and subclinical renal involvement in patients with primary Sjogren’s syndrome (pSS). Of the 174 patients screened, seventy patients with pSS underwent renal… read more here.
Keywords: primary sjogren; sjogren syndrome; rta; renal involvement ... See more keywords
Evaluation of NO2-degradation by the rubber-titanium-aluminum ultrafine grained micro-surfacing material and its effect on pavement performance
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pavement Research and Technology"
DOI: 10.1007/s42947-019-0009-0
Abstract: The preparation of high degradation rate and recyclable photocatalytic material for automobile exhaust degradation is a hot and difficult issue in the field of automobile exhaust degradation. In this paper, a modified Rubber-Titanium-Aluminum(RTA) degradation material… read more here.
Keywords: effect; degradation; rta; degradation rate ... See more keywords
Small molecule inhibitors targeting the interaction of ricin toxin A subunit with ribosomes.
Sign Up to like & getrecommendations! Published in 2020 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.0c00127
Abstract: Ricin toxin A subunit (RTA) removes an adenine from the universally conserved sarcin/ricin loop (SRL) on eukaryotic ribosomes thereby inhibiting protein synthesis. No high affinity and selective small-molecule therapeutic antidotes have been reported against ricin… read more here.
Keywords: molecule; ricin; small molecule; rta ... See more keywords
Thermochemical and Quantum Descriptor Calculations for Gaining Insight into Ricin Toxin A (RTA) Inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.0c02588
Abstract: In this work, we performed a study to assess the interactions between the ricin toxin A (RTA) subunit of ricin and some of its inhibitors using modern semiempirical quantum chemistry and ONIOM quantum mechanics/molecular mechanics… read more here.
Keywords: ricin toxin; quantum; rta; toxin rta ... See more keywords
Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c05252
Abstract: The archetype inhibitors of ferroptosis, ferrostatin-1 and liproxstatin-1, were identified via high-throughput screening of compound libraries for cytoprotective activity. These compounds have been shown to inhibit ferroptosis by suppressing propagation of lipid peroxidation, the radical… read more here.
Keywords: cell death; lipid peroxidation; intrinsic extrinsic; activity ... See more keywords
Leucine 232 and hydrophobic residues at the ribosomal P stalk binding site are critical for biological activity of ricin
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20192022
Abstract: Abstract Ricin interacts with the ribosomal P stalk to cleave a conserved adenine from the α-sarcin/ricin loop (SRL) of the rRNA. Ricin toxin A chain (RTA) uses Arg235 as the most critical arginine for binding… read more here.
Keywords: stalk; activity; ribosomal stalk; rta ... See more keywords
Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2023.2219038
Abstract: Abstract Ricin toxin A chain (RTA), from Ricinus communis, is a deadly protein that inactivates ribosomes by degrading an adenine residue at position 4324 in 28S rRNA. Recently, we have demonstrated that pterin-7-carboxamides with peptide… read more here.
Keywords: toxin chain; rta; crystal structure; ricin toxin ... See more keywords
Mental health outcomes in road traffic accident survivors: prospective cohort study
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Public Health"
DOI: 10.1093/eurpub/ckaa166.1380
Abstract: Mental health outcomes of road traffic accidents (RTAs) are always investigated amongst the injured. The aim of this study was to investigate psychological consequences and associated factors in all RTA survivors irrelevant of their injury… read more here.
Keywords: road traffic; health; rta; injury ... See more keywords
Lower Extremity Fractures in Hospitalized Pediatric Patients Following Road Traffic Accidents
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Emergency Care"
DOI: 10.1097/pec.0000000000001504
Abstract: Abstract Lower extremity fractures (LEFs) caused by road traffic accidents (RTAs) can result in significant morbidity and account for a substantial part of nonfatal injuries requiring hospitalization. This study investigated the epidemiology of RTA-associated LEFs… read more here.
Keywords: road traffic; rta; epidemiology; traffic accidents ... See more keywords
Improved Carry-in Workload Estimation for Global Multiprocessor Scheduling
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Transactions on Parallel and Distributed Systems"
DOI: 10.1109/tpds.2017.2679195
Abstract: As an important and fundamental tool for analyzing the schedulability of a real-time task set on the multiprocessor platform, response time analysis (RTA) has been researched for several years on both Global Fixed Priority (G-FP)… read more here.
Keywords: carry workload; edf scheduling; time; multiprocessor ... See more keywords
KSHV RTA Induces Degradation of the Host Transcription Repressor ID2 To Promote the Viral Lytic Cycle
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00101-22
Abstract: In addition to its transcription regulatory role, RTA is also known to have an E3 ubiquitin ligase activity, which RTA utilizes for inducing protein degradation. However, it is still largely unknown what host factors are… read more here.
Keywords: lytic cycle; kshv lytic; transcription; rta ... See more keywords