Human RTEL1 stabilizes long G-overhangs allowing telomerase-dependent over-extension
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DOI: 10.1093/nar/gky173
Abstract: Abstract Telomere maintenance protects the cell against genome instability and senescence. Accelerated telomere attrition is a characteristic of premature aging syndromes including Dyskeratosis congenita (DC). Mutations in hRTEL1 are associated with a severe form of… read more here.
Keywords: human rtel1; telomerase dependent; rtel1 stabilizes; long overhangs ... See more keywords