Comprehensive characterization of genomic and radiologic features reveals distinct driver patterns of RTK/RAS pathway in ground‐glass opacity pulmonary nodules
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DOI: 10.1002/ijc.34238
Abstract: Ground‐glass opacity (GGO)‐associated pulmonary nodules have been known as a radiologic feature of early‐stage lung cancers and exhibit an indolent biological behavior. However, the correlation between driver genes and radiologic features as well as the… read more here.
Keywords: driver; rtk ras; ggo; radiologic features ... See more keywords
RTK-RAS pathway mutation is enriched in myeloid sarcoma
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DOI: 10.1038/s41408-018-0083-6
Abstract: Myeloid sarcoma (MS), or granulocytic sarcoma, is a rare extramedullary tumor of immature myeloid cells. MS may present simultaneously with or during the course of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or any forms… read more here.
Keywords: sarcoma; myeloid sarcoma; rtk ras; cancer ... See more keywords
Abstract IA18: Somatic predisposition to germline mutations in the RTK/RAS/MAPK pathway
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DOI: 10.1158/1557-3125.ras23-ia18
Abstract: Somatic and germline mutations are traditionally viewed as separate entities. Yet, it is well established that germline variants (either inherited or occurring spontaneously) can influence cancer risk - i.e. cancer predisposition syndromes. In this presentation,… read more here.
Keywords: ras mapk; germline; mutations rtk; germline mutations ... See more keywords
Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma
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DOI: 10.3389/fonc.2022.924239
Abstract: The RTK/RAS pathway is an oncogenic signaling pathway for which many targeted drugs have been developed; however, survival remains poor. A combination of targeted therapy and immunotherapy has emerged as an option for improving cancer… read more here.
Keywords: infiltration; lung adenocarcinoma; ras pathway; rtk ras ... See more keywords