Relative telomere length impact on mortality of COVID‐19: Sex differences
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28368
Abstract: Increasing age is associated with severity and higher mortality of COVID‐19. Telomere shortening is associated with higher risk of infections and may be used to identify those patients who are more likely to die. We… read more here.
Keywords: telomere length; rtl; mortality; mortality covid ... See more keywords
Correlation between metabolic syndrome and relative telomere length shortening in HIV/AIDS patients on combined antiretroviral therapy
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111269
Abstract: BACKGROUND Components of the metabolic syndrome (MetS) play an important role in the accelerated aging process. Relative telomere length (RTL) is a marker of biological aging. The aim of our study was to determine RTL… read more here.
Keywords: relative telomere; rtl; telomere length; shortening hiv ... See more keywords
The association between early‐life relative telomere length and childhood neurodevelopment
Sign Up to like & getrecommendations! Published in 2018 at "Neurotoxicology"
DOI: 10.1016/j.neuro.2018.01.005
Abstract: HighlightsThere was no clear association between relative telomere length, and neurodevelopmental outcomes in this study population.The majority of the outcomes show a slight, positive association with relative telomere length, although results are imprecise.Cord blood rTL… read more here.
Keywords: relative telomere; rtl; telomere length; neurodevelopmental outcomes ... See more keywords
Leukocyte telomere length, lipid parameters and gestational diabetes risk: a case-control study in a Chinese population
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-44968-9
Abstract: Telomere length (TL) is linked to various age-related diseases, but little is known about telomeres in gestational diabetes mellitus (GDM). We surveyed 509 subjects (113 GDM patients and 396 frequency matched controls) in Nanjing Drum… read more here.
Keywords: gestational diabetes; rtl; telomere length; gdm risk ... See more keywords
RTL Conversion Method From Pipelined Synchronous RTL Models Into Asynchronous Ones
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Access"
DOI: 10.1109/access.2022.3158487
Abstract: In this paper, we propose a conversion method from pipelined synchronous Register Transfer Level (RTL) models into pipelined asynchronous RTL models with bundled-data implementation. To know data-path resources controlled by each pipeline stage, the proposed… read more here.
Keywords: optimization methods; rtl; conversion; rtl models ... See more keywords
SimuNN: A Pre-RTL Inference, Simulation and Evaluation Framework for Neural Networks
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Journal on Emerging and Selected Topics in Circuits and Systems"
DOI: 10.1109/jetcas.2020.2993854
Abstract: Neural networks have been widely deployed in a number of applications due to their strong learning and feature extraction ability. To meet the ever increasing accuracy requirements from various applications, neural network models have become… read more here.
Keywords: pre rtl; inference simulation; hardware; neural networks ... See more keywords
Drivers of longitudinal telomere dynamics in the long-lived bat species, Myotis myotis.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular ecology"
DOI: 10.1111/mec.15395
Abstract: Age related telomere shortening is considered a hallmark of the ageing process. However, a recent cross-sectional ageing study of relative telomere length (rTL) in bats failed to detect a relationship between rTL and age in… read more here.
Keywords: myotis myotis; myotis; rtl; age ... See more keywords
Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes
Sign Up to like & getrecommendations! Published in 2022 at "BMC Cancer"
DOI: 10.1186/s12885-022-09221-z
Abstract: Background Telomeres are protective structures at chromosome ends which shorten gradually with increasing age. In chronic lymphocytic leukemia (CLL), short telomeres have been associated with unfavorable disease outcome, but the link between clonal evolution and… read more here.
Keywords: telomere length; tp53; evol tp53; rtl ... See more keywords
Telomere in colorectal cancer associated with distant metastases and predicted a poor prognosis
Sign Up to like & getrecommendations! Published in 2021 at "Translational Cancer Research"
DOI: 10.21037/tcr-20-3341
Abstract: Background Telomere is essential for chromosomal stability and its length has been proven to be related to prognosis in many malignant tumors. This study aims to investigate the relevance of telomere length with clinical and… read more here.
Keywords: cancer; distant metastases; cell; adenoma cells ... See more keywords
C-peptide is a predictor of telomere shortening: A five-year longitudinal study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.978747
Abstract: Aim Relative telomere length (RTL) predicts the development of many age-related diseases. Yet, few studies have evaluated their longitudinal effect on RTL. We investigated longitudinally the association between cardiometabolic risk factors and RTL. Methods This… read more here.
Keywords: telomere shortening; year; rtl; shorter rtl ... See more keywords
Internalizing Mental Disorders and Accelerated Cellular Aging Among Perinatally HIV-Infected Youth in Uganda
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00705
Abstract: Introduction: Internalizing mental disorders (IMDs) in HIV+ children and adolescents are associated with impaired quality of life and non-adherence to anti-retroviral treatment. Telomere length is a biomarker of cellular aging, and shorter telomere length has… read more here.
Keywords: imds; internalizing mental; cellular aging; rtl ... See more keywords