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RTL1/PEG11 imprinted in human and mouse brain mediates anxiety-like and social behaviors and regulates neuronal excitability in the locus coeruleus

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Published in 2022 at "Human Molecular Genetics"

DOI: 10.1093/hmg/ddac110

Abstract: Abstract RTL1/PEG11, which has been associated with anxiety disorders, is a retrotransposon-derived imprinted gene in the placenta. However, imprinting patterns and functions of RTL1 in the brain have not been well-investigated. We found Rtl1 was… read more here.

Keywords: locus coeruleus; neuronal excitability; brain mediates; brain ... See more keywords