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   Articles with "rtn4" as a keyword



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Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity.

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recommendations! Published in 2017 at "Chemical communications"

DOI: 10.1039/c7cc01480e

Abstract: Chemical genetics has arisen as a powerful approach for identifying novel anti-cancer agents. However, a major bottleneck of this approach is identifying the targets of lead compounds that arise from screens. Here, we coupled the… read more here.

Keywords: reticulon; colorectal cancer; pathogenicity; cancer ... See more keywords
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Exosomes derived from circRNA Rtn4-modified BMSCs attenuate TNF-α-induced cytotoxicity and apoptosis in murine MC3T3-E1 cells by sponging miR-146a

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recommendations! Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20193436

Abstract: Abstract Osteoporosis is the most common and complex skeletal disorder worldwide. Exosomes secreted by bone marrow-derived mesenchymal stromal cells (BMSCs) are considered as an ideal seed source for bone tissue regeneration. However, the role of… read more here.

Keywords: mir 146a; caspase; tnf; apoptosis ... See more keywords
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RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction

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recommendations! Published in 2022 at "Autophagy"

DOI: 10.1080/15548627.2022.2047344

Abstract: ABSTRACT Cerebral infarction induces angiogenesis in the thalamus and influences functional recovery. The mechanisms underlying angiogenesis remain unclear. This study aimed to investigate the role of RTN4/Nogo-A in mediating macroautophagy/autophagy and angiogenesis in the thalamus… read more here.

Keywords: vascular autophagy; rtn4; thalamus; angiogenesis ... See more keywords
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Impact of RTN4 gene polymorphism and its plasma level on susceptibility to nasopharyngeal carcinoma

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recommendations! Published in 2019 at "Medicine"

DOI: 10.1097/md.0000000000017831

Abstract: Abstract The RTN4 gene plays a role in the development and progression of cancer. This case–control study aimed to investigate the association between the RTN4 gene polymorphism and its plasma level with the risk of… read more here.

Keywords: plasma level; polymorphism; rtn4 gene; rtn4 ... See more keywords