Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.12338
Abstract: Abstract Purpose/Objectives For lung stereotactic body radiation therapy (SBRT), real‐time tumor tracking (RTT) allows for less radiation to normal lung compared to the internal target volume (ITV) method of respiratory motion management. To quantify the… read more here.
Keywords: risk; rtt; volume; radiation pneumonitis ... See more keywords
Dietary intake and growth deficits in Rett syndrome—A cross‐section study
Sign Up to like & getrecommendations! Published in 2021 at "Autism Research"
DOI: 10.1002/aur.2508
Abstract: Growth deficit is a common comorbidity and one of the supportive criteria in Rett syndrome (RTT). This study aimed to investigate the impact of dystonia, dietary intakes, and clinical severities on growth patterns in a… read more here.
Keywords: rtt; rett syndrome; study; rtt specific ... See more keywords
Design and outcome measures of LAVENDER, a phase 3 study of trofinetide for Rett syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Contemporary clinical trials"
DOI: 10.1016/j.cct.2022.106704
Abstract: INTRODUCTION Rett syndrome (RTT) is a debilitating neurodevelopmental disorder with no approved treatments. Trofinetide is a synthetic analog of glycine-proline-glutamate, the N-terminal tripeptide of insulin-like growth factor 1. In a phase 2, placebo-controlled trial in… read more here.
Keywords: study; outcome measures; rett syndrome; phase ... See more keywords
Atypical processing of tones and phonemes in Rett Syndrome as biomarkers of disease progression
Sign Up to like & getrecommendations! Published in 2020 at "Translational Psychiatry"
DOI: 10.1038/s41398-020-00877-4
Abstract: Due to severe motor impairments and the lack of expressive language abilities seen in most patients with Rett Syndrome (RTT), it has proven extremely difficult to obtain accurate measures of auditory processing capabilities in this… read more here.
Keywords: rtt; rett syndrome; processing tones; tones phonemes ... See more keywords
Disruption of MeCP2–TCF20 complex underlies distinct neurodevelopmental disorders
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119078119
Abstract: Significance Loss-of-function mutations in MECP2 cause the neurological disorder Rett syndrome (RTT), but the precise molecular mechanism driving pathogenesis remains unclear. Using an unbiased approach to identify proteins that interact with MeCP2, we identified the… read more here.
Keywords: rtt; function; mecp2 tcf20; tcf20 complex ... See more keywords
O050 Utility of ramp test time in patients undergoing assessment for renal transplantation
Sign Up to like & getrecommendations! Published in 2023 at "British Journal of Surgery"
DOI: 10.1093/bjs/znad101.050
Abstract: Prior to renal transplant listing, cardiovascular screening is performed to stratify the risk of cardiovascular disease (CVD). During pre-assessment in our centre, patients undergo a ramp test (a timed assessment to walk 130m), which is… read more here.
Keywords: assessment; test; transplantation; test time ... See more keywords
IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddw384
Abstract: Rett syndrome (RTT) is an X-linked neurodevelopmental disorder in which the MECP2 (methyl CpG-binding protein 2) gene is mutated. Recent studies showed that RTT-derived neurons have many cellular deficits when compared to control, such as:… read more here.
Keywords: rtt; igf1 neuronal; derived neurons; mecp2 ... See more keywords
S66. USING UNITIZATION TO CIRCUMVENT RELATIONAL MEMORY DEFICITS IN SCHIZOPHRENIA
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa031.132
Abstract: Abstract Background Relational memory (RM) is disproportionately affected in schizophrenia. Unitization is a cognitive strategy that compensates for RM deficits by facilitating the combination of disparate pieces of information to form a single functional unit.… read more here.
Keywords: rtt; task; control; group ... See more keywords
Biliary Tract Disease in Girls and Young Women With Rett Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000002273
Abstract: Objective: We reviewed medical records and conducted a nationwide survey to characterize the clinical features and determine the prevalence of biliary tract disease in girls and women with Rett syndrome (RTT). Methods: Sixty-two individuals with… read more here.
Keywords: rtt; biliary tract; rett syndrome; tract disease ... See more keywords
Multimodal Retransmission Timer for LPWAN
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Internet of Things Journal"
DOI: 10.1109/jiot.2020.2971609
Abstract: Low-power wide-area networks (LPWANs) are experiencing high momentum as an inexpensive solution for enabling the Internet-of-Things (IoT) applications. Recent Internet connectivity support developments are expected to further fuel the adoption of LPWAN. However, the latter… read more here.
Keywords: lpwan; rtt; rto; multimodal retransmission ... See more keywords
Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice
Sign Up to like & getrecommendations! Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aau0164
Abstract: KCC2 expression–enhancing small molecules rescue cellular and behavior deficits in human RTT neurons and Mecp2 mutant mice. Restoring balance in Rett syndrome Rett syndrome (RTT) is a neurodevelopmental disorder causing cognitive, motor, and emotional impairments.… read more here.
Keywords: rtt; rett syndrome; expression; mecp2 mutant ... See more keywords