Evaluation of Clinical Relevance and Biological Effects of Antirituximab Antibodies in Patients With Pemphigus.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.2149
Abstract: Importance The clinical relevance of antirituximab antibodies (ARAs) in patients with pemphigus who are treated with rituximab (RTX) is currently unknown. Objective To determine the prevalence of ARAs in patients with pemphigus who are treated… read more here.
Keywords: patients pemphigus; antirituximab antibodies; cell depletion; rtx ... See more keywords
Single‐dose versus low‐dose rituximab in corticosteroid‐resistant or relapsed ITP: A multicenter, randomized, controlled study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26473
Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder, in which rituximab (RTX) induces the best long‐term effect among recommended second‐line treatments. Nevertheless, the optimal regimen of RTX remains unclear. We herein conducted a prospective,… read more here.
Keywords: relapsed itp; resistant relapsed; low dose; corticosteroid resistant ... See more keywords
Secondary rituximab‐associated versus primary immunodeficiencies: The enigmatic border
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149667
Abstract: Rituximab (RTX), a chimeric monoclonal antibody targeting CD20‐positive cells, is a valuable treatment option for malignant and benign immune‐related disorders. The rationale of targeting the CD20 antigen relies on depletion of both healthy and autoreactive/malignant… read more here.
Keywords: cell; rtx; secondary rituximab; hypogammaglobulinemia ... See more keywords
Longitudinal Effects of Single Hindlimb Radiation Therapy on Bone Strength and Morphology at Local and Contralateral Sites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3289
Abstract: Radiation therapy (RTx) is associated with increased risk for late‐onset fragility fractures in bone tissue underlying the radiation field. Bone tissue outside the RTx field is often selected as a “normal” comparator tissue in clinical… read more here.
Keywords: strength; radiation therapy; field; bone ... See more keywords
Rituximab for refractory eosinophilic fasciitis: a case series with long-term follow-up and literature review
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology International"
DOI: 10.1007/s00296-021-04887-3
Abstract: RTX could be an effective and safe alternative treatment for refractory EF. Rituximab (RTX) is a successful therapeutic option for various autoimmune diseases. Our aim is to report our experience with RTX in eosinophilic fasciitis… read more here.
Keywords: rheumatology; literature review; rtx; eosinophilic fasciitis ... See more keywords
Efficacy of rituximab in patients with Graves’ orbitopathy: a retrospective multicenter nationwide study
Sign Up to like & getrecommendations! Published in 2020 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-020-04651-6
Abstract: Purpose The clinical utility of rituximab (RTX) in Graves’ orbitopathy (GO) treatment remains controversial since the discrepant results from 2 prospective randomized studies (Stan M et al. J Clin Endocrinol Metab 2015; Salvi M et… read more here.
Keywords: rituximab; week; treatment; study ... See more keywords
Combination therapy of rituximab and mycophenolate mofetil in childhood lupus nephritis
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3767-4
Abstract: BackgroundIn clinical trials, the addition of rituximab (RTX) to the combination therapeutic regimen of mycophenolate mofetil (MMF) and corticosteroids failed to improve outcome in lupus nephritis (LN). However, recent data suggest that RTX may have… read more here.
Keywords: rituximab; combination; lupus nephritis; rtx ... See more keywords
Immunoglobulin serum levels in rituximab-treated patients with steroid-dependent nephrotic syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Nephrology"
DOI: 10.1007/s00467-019-04398-1
Abstract: Background Rituximab (RTX) is efficient in steroid-dependent nephrotic syndrome (SDNS) in pediatric and adult patients. The aim of this study is to describe hypogammaglobulinemia as a side effect of RTX treatment. Methods All pediatric patients… read more here.
Keywords: nephrology; age; steroid dependent; rtx ... See more keywords
Rituximab in connective tissue disease–associated interstitial lung disease
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04557-7
Abstract: Introduction/objectivesTo evaluate rituximab (RTX) effectiveness and safety in patients with interstitial lung disease (ILD) related to connective tissue diseases (CTD).MethodsRetrospective multicenter cohort study, including patients with CTD-ILD, followed in six Portuguese rheumatology departments until November… read more here.
Keywords: connective tissue; lung disease; disease; interstitial lung ... See more keywords
Should rituximab be administered before cyclophosphamide as a first-line steroid-sparing agent to young children with steroid-dependent nephrotic syndrome?
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-020-01938-0
Abstract: Since the 1970s, cyclophosphamide (CPM) has been the most commonly used first-line steroid-sparing agents (SPA) in the treatment of frequent-relapsing and steroid-dependent nephrotic syndrome (FR/SDNS) among pediatric nephrologist across the world. In a recent study… read more here.
Keywords: first line; cpm; group; rtx ... See more keywords
Resiniferatoxin Hampers the Nocifensive Response of Caenorhabditis elegans to Noxious Heat, and Pathway Analysis Revealed that the Wnt Signaling Pathway is Involved.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03471-2
Abstract: Resiniferatoxin (RTX) is a metabolite extracted from Euphorbia resinifera. RTX is a potent capsaicin analog with specific biological activities resulting from its agonist activity with the transient receptor potential channel vanilloid subfamily member 1 (TRPV1).… read more here.
Keywords: wnt signaling; elegans noxious; noxious heat; nocifensive response ... See more keywords