Rubiscolin-6 activates opioid receptors to enhance glucose uptake in skeletal muscle.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food and drug analysis"
DOI: 10.1016/j.jfda.2018.06.012
Abstract: Rubiscolin-6 is an opioid peptide derived from plant ribulose bisphosphate carboxylase/oxygenase (Rubisco). It has been demonstrated that opioid receptors could control glucose homeostasis in skeletal muscle independent of insulin action. Therefore, Rubiscolin-6 may be involved… read more here.
Keywords: skeletal muscle; uptake skeletal; rubiscolin; glucose uptake ... See more keywords
Rubiscolin-6, a δ-Opioid Peptide from Spinach RuBisCO, Exerts Antidepressant-Like Effect in Restraint-Stressed Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.65.202
Abstract: Rubiscolin-6 (Tyr-Pro-Leu-Asp-Leu-Phe) is produced by a pepsin digest of spinach d-ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and known to act as an agonist on δ-opioid receptor. Here, we showed that administration of rubiscolin-6 reduced immobility time in the… read more here.
Keywords: restraint stressed; rubiscolin; like effect; stressed mice ... See more keywords
Rubiscolin-6 rapidly suppresses the postprandial motility of the gastric antrum and subsequently increases food intake via δ-opioid receptors in mice
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12856
Abstract: Rubiscolin-6 is a food-derived opioid peptide found in Spinacia oleracea that has anti-nociceptive, memory-enhancing, anxiolytic-like and anti-depressant effects. Rubiscolin-6 has been reported to have two opposing effects on food intake. Food intake is closely connected… read more here.
Keywords: rubiscolin; food; motility; gastric antrum ... See more keywords