Aza-Rubottom Oxidation: Synthetic Access to Primary α-Aminoketones.
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DOI: 10.1021/jacs.8b13818
Abstract: An aza analogue of the Rubottom oxidation is reported. This facile transformation takes place at ambient temperature and directly converts silyl enol ethers to the corresponding primary α-aminoketones. The use of hexafluoroisopropanol (HFIP) as the… read more here.
Keywords: aza rubottom; rubottom oxidation; oxidation synthetic; primary aminoketones ... See more keywords