RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin.
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DOI: 10.1038/s41467-022-28952-y
Abstract: The small GTPase ARL8 associates with endolysosomes, leading to the recruitment of several effectors that couple endolysosomes to kinesins for anterograde transport along microtubules, and to tethering factors for eventual fusion with other organelles. Herein… read more here.
Keywords: arl8 effectors; effectors promote; dynein dynactin; rufy3 rufy4 ... See more keywords