Cas3-stimulated runaway replication of modified ColE1 plasmids in Escherichia coli is temperature dependent.
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DOI: 10.1093/femsle/fnz106
Abstract: The clustered regularly interspersed short palindromic repeats (CRISPR)-Cas system constitutes an adaptive immunity system of prokaryotes against mobile genetic elements using a CRISPR RNA (crRNA)-mediated interference mechanism. In Type I CRISPR-Cas systems, crRNA guided by… read more here.
Keywords: plasmid replication; cas3 stimulated; crispr cas; runaway replication ... See more keywords