The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms
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DOI: 10.1038/s41598-022-07391-1
Abstract: Soluble guanylate cyclase (sGC) requires a heme-group bound in order to produce cGMP, a second messenger involved in memory formation, while heme-free sGC is inactive. Two compound classes can increase sGC activity: sGC stimulators acting… read more here.
Keywords: runcaciguat; sgc; memory; bay 747 ... See more keywords