Identification of runs of homozygosity in Western honey bees (Apis mellifera) using whole‐genome sequencing data
Sign Up to like & getrecommendations! Published in 2023 at "Ecology and Evolution"
DOI: 10.1002/ece3.9723
Abstract: Abstract Runs of homozygosity (ROH) are continuous homozygous segments that arise through the transmission of haplotypes that are identical by descent. The length and distribution of ROH segments provide insights into the genetic diversity of… read more here.
Keywords: apis mellifera; honey bees; roh; whole genome ... See more keywords
Runs of homozygosity: windows into population history and trait architecture
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Genetics"
DOI: 10.1038/nrg.2017.109
Abstract: Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding gives rise to such autozygosity; however, genome-wide data… read more here.
Keywords: homozygosity windows; windows population; runs homozygosity; history ... See more keywords
Whole-genome SNP markers reveal runs of homozygosity in indigenous cattle breeds of Pakistan.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2026369
Abstract: The runs of homozygosity (ROH) were identified in 14 Pakistani cattle breeds (n = 105) by genotyping with the Illumina 50 K SNP BeadChip. These breeds were categorized into Dairy, Dual, and Draft breeds based on their utility… read more here.
Keywords: whole genome; genome snp; cattle breeds; runs homozygosity ... See more keywords
Analysis of Runs of Homozygosity of cattle living in different climate zones.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of animal science"
DOI: 10.1093/jas/skad061
Abstract: Aim of this study was to analyze the distribution and characteristics of runs of homozygosity in Bos taurus taurus and Bos taurus indicus breeds, as well as their crosses, farmed all around the word. With… read more here.
Keywords: temperate; taurus; analysis; indicus ... See more keywords
Runs of homozygosity: current knowledge and applications in livestock.
Sign Up to like & getrecommendations! Published in 2017 at "Animal genetics"
DOI: 10.1111/age.12526
Abstract: This review presents a broader approach to the implementation and study of runs of homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH and their practical implications. ROH are continuous homozygous segments that… read more here.
Keywords: information; homozygosity; runs homozygosity; homozygosity current ... See more keywords
Genome-wide scan for runs of homozygosity in Asian wild boars and Anqing six-end-white pigs.
Sign Up to like & getrecommendations! Published in 2022 at "Animal genetics"
DOI: 10.1111/age.13250
Abstract: Inbreeding and loss of genetic diversity are serious problems in local Chinese pig breeds. Runs of homozygosity (ROHs) are contiguous lengths of homozygous genotypes that can provide information on inbreeding levels, mating schemes, selection pressure,… read more here.
Keywords: anqing six; asian wild; homozygosity; six end ... See more keywords
Genome‐wide survey on three local horse populations with a focus on runs of homozygosity pattern
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Animal Breeding and Genetics"
DOI: 10.1111/jbg.12680
Abstract: Abstract Purosangue Orientale Siciliano, Sanfratellano and Siciliano represent the Sicilian equine genetic resource. This study aimed to investigate the genetic diversity, population structure and the pattern of autozygosity of Sicilian horse populations using genome‐wide single‐nucleotide… read more here.
Keywords: purosangue orientale; genome wide; horse populations; siciliano ... See more keywords
Runs of homozygosity reveal past bottlenecks and contemporary inbreeding across diverging populations of an island‐colonizing bird
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Ecology"
DOI: 10.1111/mec.16865
Abstract: Genomes retain evidence of the demographic history and evolutionary forces that have shaped populations and drive speciation. Across island systems, contemporary patterns of genetic diversity reflect population demography, including colonization events, bottlenecks, gene flow and… read more here.
Keywords: diverging populations; roh; diversity; across diverging ... See more keywords
Copy number variant and runs of homozygosity detection by microarrays enabled more precise molecular diagnoses in 11,020 clinical exome cases
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DOI: 10.1186/s13073-019-0639-5
Abstract: BackgroundExome sequencing (ES) has been successfully applied in clinical detection of single nucleotide variants (SNVs) and small indels. However, identification of copy number variants (CNVs) using ES data remains challenging. The purpose of this study… read more here.
Keywords: molecular diagnoses; copy number; detection; runs homozygosity ... See more keywords
The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds
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DOI: 10.1371/journal.pone.0176780
Abstract: Domestication and the subsequent selection of animals for either economic or morphological features can leave a variety of imprints on the genome of a population. Genomic regions subjected to high selective pressures often show reduced… read more here.
Keywords: breed; runs homozygosity; selection; roh ... See more keywords
Artificial selection increased body weight but induced increase of runs of homozygosity in Hanwoo cattle
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0193701
Abstract: Artificial selection has been demonstrated to have a rapid and significant effect on the phenotype and genome of an organism. However, most previous studies on artificial selection have focused solely on genomic sequences modified by… read more here.
Keywords: runs homozygosity; artificial selection; increase; selection ... See more keywords