Xanthoma disseminatum in a patient with RUNX1‐mutated acute myelogenous leukemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Dermatology"
DOI: 10.1111/ijd.16414
Abstract: hCG diet to avoid unnecessary drug discontinuation. ISO could be reinstituted only when the b-hCG level is normalized on careful reassessment. Despite the general concept of ISO teratogenicity, the risk of MM secondary to periconceptional… read more here.
Keywords: xanthoma disseminatum; patient runx1; disseminatum patient; pregnancy ... See more keywords
RUNX1 Mutations Identify an Entity of Blast Phase Chronic Myeloid Leukemia (BP-CML) Patients with Distinct Phenotype, Transcriptional Profile and Drug Vulnerabilities
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DOI: 10.1182/blood-2018-99-111602
Abstract: Introduction: Genetic alterations of RUNX1 gene (mutations and fusion genes) are common in hematological malignancies including AML, ALL, MDS, and MPN. Mutations of RUNX1 occur in 10% of newly diagnosed AML patients and associate with… read more here.
Keywords: runx1; runx1 mutations; runx1 mutated; research funding ... See more keywords
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
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DOI: 10.1182/bloodadvances.2019000901
Abstract: First reported in 1999, germline runt-related transcription factor 1 (RUNX1) mutations are a well-established cause of familial platelet disorder with predisposition to myeloid malignancy (FPD-MM). We present the clinical phenotypes and genetic mutations detected in… read more here.
Keywords: germline runx1; heterogeneity; runx1; runx1 mutated ... See more keywords