The RUNX1/RUNX1T1 network: translating insights into therapeutic options
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DOI: 10.1016/j.exphem.2020.11.005
Abstract: Highlights • A RUNX1/RUNX1T1-associated gene expression network drives acute myeloid leukemia.• RUNX1/RUNX1T1 dysregulates gene expression at multiple levels.• Interrogation of the RUNX1/RUNX1T1 network by RNA interference or CRISPR screens identifies novel therapeutic targets.• RUNX1/RUNX1T1 drives… read more here.
Keywords: network translating; runx1 runx1t1; runx1t1 network; translating insights ... See more keywords