Runx3 plays a critical role in restriction-point and defense against cellular transformation
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DOI: 10.1038/onc.2017.290
Abstract: The restriction (R)-point decision is fundamental to normal differentiation and the G1–S transition, and the decision-making machinery is perturbed in nearly all cancer cells. The mechanisms underlying the cellular context–dependent R-point decision remain poorly understood.… read more here.
Keywords: plays critical; critical role; point; runx3 plays ... See more keywords