Detection of ALK rearrangements in 4002 Russian patients: The utility of different diagnostic approaches.
Sign Up to like & getrecommendations! Published in 2017 at "Lung cancer"
DOI: 10.1016/j.lungcan.2016.11.001
Abstract: BACKGROUND Clinical guidelines highly recommended the detection of potentially targetable genetic aberrations such as anaplastic lymphoma kinase (ALK) rearrangements in patients with non-small cell lung cancer (NSCLC). Few methods, such as the ALK break apart… read more here.
Keywords: detection; alk; ihc fish; russian patients ... See more keywords
Microsatellite Instability in Russian Patients with Colorectal Cancer
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DOI: 10.3390/ijms23137062
Abstract: The aim of this study was to determine the characteristics of Russian patients with microsatellite instability (MSI) tumors. MSI in the tumor was determined in 514 patients with colon cancer using PCR and subsequent fragment… read more here.
Keywords: microsatellite instability; russian patients; status; stage ... See more keywords
Specificities of the DMD Gene Mutation Spectrum in Russian Patients
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DOI: 10.3390/ijms232112710
Abstract: Duchenne/Becker muscular dystrophy (DMD/BMD) is the most common form of muscular dystrophy, accounting for over 50% of all cases. In this regard, in Russia we carry out a program of selective screening for DMD/BMD, which… read more here.
Keywords: russian patients; dmd gene; gene; mutation spectrum ... See more keywords
Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis
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DOI: 10.3390/jpm12040641
Abstract: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease and its treatment is an urgent problem of rheumatology. Olokizumab (OKZ) is a new humanized monoclonal antibody targeting IL-6 and is one of the few promising… read more here.
Keywords: clinical factors; hla; russian patients; rheumatoid arthritis ... See more keywords
Lack of association between mitochondrial DNA haplogroups J and T and clinical manifestation in Russian patients with Brugada syndrome.
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DOI: 10.3892/br.2020.1324
Abstract: Brugada syndrome (BrS) is an inherited disorder characterized by specific ST segment elevation in the right precordial leads, pseudo right bundle branch block, and a high risk of sudden cardiac death due to ventricular tachycardia.… read more here.
Keywords: manifestation; brs; mtdna; russian patients ... See more keywords