LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "rutaecarpine" as a keyword



Photo from wikipedia

Time effect of rutaecarpine on caffeine pharmacokinetics in rats

Sign Up to like & get
recommendations! Published in 2021 at "Biochemistry and Biophysics Reports"

DOI: 10.1016/j.bbrep.2021.101121

Abstract: Rutaecarpine is reported as a potent inducer of CYP1A2 enzyme in rats. There are natural herbal supplements containing rutaecarpine that are designed to enhance the CYP1A2-dependent removal of caffeine from blood so that people can… read more here.

Keywords: effect rutaecarpine; caffeine; time; cyp1a2 ... See more keywords
Photo by andreacaramello from unsplash

Dual-targeting Rutaecarpine-NO donor hybrids as novel anti-hypertensive agents by promoting release of CGRP.

Sign Up to like & get
recommendations! Published in 2019 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2019.02.037

Abstract: CGRP, known as the most potent vasodilator substance, plays an important role in hypertension initiation and development. TRPV1 and TRPA1 are critical in promoting the synthesis and release of CGRP, thereby regulating the cardiovascular tone.… read more here.

Keywords: release cgrp; anti hypertensive; novel anti; rutaecarpine ... See more keywords
Photo from wikipedia

Rutaecarpine Inhibits U87 Glioblastoma Cell Migration by Activating the Aryl Hydrocarbon Receptor Signaling Pathway

Sign Up to like & get
recommendations! Published in 2021 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2021.765712

Abstract: Glioblastoma is the most frequent and aggressive primary astrocytoma in adults. The high migration ability of the tumor cells is an important reason for the high recurrence rate and poor prognosis of glioblastoma. Recently, emerging… read more here.

Keywords: glioblastoma; aryl hydrocarbon; migration; signaling pathway ... See more keywords
Photo by nci from unsplash

Rutaecarpine suppresses the proliferation and metastasis of colon cancer cells by regulating the STAT3 signaling

Sign Up to like & get
recommendations! Published in 2022 at "Journal of Cancer"

DOI: 10.7150/jca.66177

Abstract: Colorectal cancer (CRC) is a malignant disease that is a serious threat to human health. Rutaecarpine (RUT) is an important bioactive alkaloid of Evodia rutaecarpa. According to previous studies, RUT suppressed the proliferation of several… read more here.

Keywords: crc cells; rut; rutaecarpine; stat3 signaling ... See more keywords