Ruthenium(II)-diphosphine complexes containing acylthiourea ligands are effective against lung and breast cancers.
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DOI: 10.1039/d1dt02851k
Abstract: We have synthesized and characterized three new ruthenium(II) diphosphine complexes containing an acylthiourea ligand, with the general formula [Ru(DPEPhos)(O,S)(bipy)]PF6, where DPEPhos = bis(2-(diphenylphosphino)phenyl)ether, bipy = 2,2'-bipyridine, and O,S = N,N-dimethyl-N'-(benzoyl)thiourea (1), N,N-dimethyl-N'-(furoyl)thiourea (2), and N,N-dimethyl-N'-(thiophenyl)thiourea… read more here.
Keywords: cancer; lung; breast; complexes containing ... See more keywords