Anticancer evaluation of ruthenium(III) complexes with N-donor ligands tethered to coumarin or uracil moieties
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.04.018
Abstract: Abstract In this study, the synthesis and characterization of new paramagnetic ruthenium(III) complexes: cis-[RuCl2(urdpa)] (1) {Hurdpa = 6-((bis(pyridin-2-ylmethyl)amino)methyl)uracil} and fac-[RuCl3(chrdpa)] (2) {chrdpa = 4-((bis(pyridin-2-ylmethyl)amino)methyl)-7-methoxycoumarin} are reported. These metal complexes have been comprehensively characterized by an array of physicochemical techniques… read more here.
Keywords: ruthenium iii; ruthenium; evaluation ruthenium; iii complexes ... See more keywords
Ruthenium(III) hydrazone complexes with triphenylphosphine/triphenylarsine co-ligands: Synthesis, DNA/BSA binding, antioxidative and cytotoxic activity
Sign Up to like & getrecommendations! Published in 2021 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2021.120532
Abstract: Abstract New ruthenium(III) complexes with (E)-3-methoxy-N'-(phenyl(pyridin-2-yl)methylene) benzohydrazide (HL) have been synthesized and characterized by various physico-chemical and spectroscopic methods. The ligand acted as a tridentate, monobasic chelating ligand with NNO donor sites in all the… read more here.
Keywords: bsa binding; ruthenium iii; dna; spectroscopy ... See more keywords
Pyridine Ruthenium(III) complexes entrapped in liposomes with enhanced cytotoxic properties in PC-3 prostate cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.02.009
Abstract: Abstract The first aim of the present study is the development of a new ruthenium(III) complex, belonging to NAMI-A class, with a potentially high cytotoxic ability. The presence of a fully protected sugar moiety as… read more here.
Keywords: cytotoxic; ruthenium iii; ability; ruthenium ... See more keywords
Ruthenium(III) complexes with imidazole ligands that modulate the aggregation of the amyloid-β peptide via hydrophobic interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2020.111303
Abstract: Alzheimer's disease (AD) is the most common form of dementia, characterized by extracellular protein deposits, comprised primarily of the peptide amyloid-beta (Aβ), are a pathological indicator of the disease. Commonly known as Aβ plaques, these… read more here.
Keywords: aggregation; hydrophobic interactions; iii complexes; ruthenium iii ... See more keywords
Ruthenium(III) 2-(aminofluoreneazo)phenolate complexes: Synthesis, characterization, catalytic activity in amidation reaction and Fluorescence quenching studies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2020.121408
Abstract: Abstract A series of ruthenium(III)2-(aminofluoreneazo)phenolate complexes with general formula [RuCl(PPh3)2(L1-5)] (1–5) (L = 2-(aminofluoreneazo)phenolate ligands) have been synthesized. The characterization of the synthesized complexes was accomplished by elemental analysis, spectroscopic (FT-IR, UV–Vis, Fluorescence and EPR) and ESI-MStechniques.… read more here.
Keywords: aminofluoreneazo phenolate; iii aminofluoreneazo; fluorescence; aminofluoreneazo ... See more keywords
Ruthenium(iii) polyethyleneimine complexes for bifunctional ammonia production and biomass upgrading
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry A"
DOI: 10.1039/c9ta10267a
Abstract: The electrocatalytic nitrogen reduction reaction is coupled with 5-hydroxymethylfurfural (HMF) oxidation, forming a unique and superior combination. read more here.
Keywords: polyethyleneimine complexes; bifunctional ammonia; ammonia production; ruthenium iii ... See more keywords
Cytotoxic cis-ruthenium(III) bis(amidine) complexes.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d3dt00328k
Abstract: In chemotherapy, the search for ruthenium compounds as alternatives to platinum compounds is proposed because of their unique properties. However, the geometry effect of ruthenium complexes is sparely investigated. In this paper, we report the… read more here.
Keywords: ruthenium iii; bis amidine; ruthenium; iii bis ... See more keywords
Structural feature of calf thymus deoxyribonucleic acid–ruthenium(III) interaction in aqueous solution by difference Fourier transformed infrared spectroscopy
Sign Up to like & getrecommendations! Published in 2017 at "Spectroscopy Letters"
DOI: 10.1080/00387010.2017.1350720
Abstract: ABSTRACT Here is the report on the interaction of ruthenium(III) species with DNA in aqueous solution at pH 7.42 by Fourier transformed infrared difference spectroscopy. Under the physiological pH and molar ratio [Ruthenium]/[DNA] = 1/80–1/20 direct binding… read more here.
Keywords: ruthenium; ruthenium iii; spectroscopy; fourier transformed ... See more keywords
Anticancer Ruthenium(III) Complexes and Ru(III)-Containing Nanoformulations: An Update on the Mechanism of Action and Biological Activity
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceuticals"
DOI: 10.3390/ph12040146
Abstract: The great advances in the studies on metal complexes for the treatment of different cancer forms, starting from the pioneering works on platinum derivatives, have fostered an increasingly growing interest in their properties and biomedical… read more here.
Keywords: iii; iii complexes; ruthenium iii; containing nanoformulations ... See more keywords