Ruxolitinib/nilotinib cotreatment inhibits leukemia-propagating cells in Philadelphia chromosome-positive ALL
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DOI: 10.1186/s12967-017-1286-5
Abstract: BackgroundAs one of the major treatment obstacles in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL), relapse of Ph+ALL may result from the persistence of leukemia-propagating cells (LPCs). Research using a xenograft mouse assay recently determined that… read more here.
Keywords: propagating cells; ruxolitinib nilotinib; chromosome positive; philadelphia chromosome ... See more keywords