Rapid and sustained antidepressant effects of resolvin D1 and D2 in a chronic unpredictable stress model
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.06.010
Abstract: Resolvin D1 (RvD1) and D2 (RvD2) are lipid mediators that are derived from docosahexaenoic acid. We recently demonstrated that intracerebroventricular (i.c.v.) infusions of RvD1 or RvD2 attenuate lipopolysaccharide-induced depression-like behaviors via mammalian target of rapamycin… read more here.
Keywords: rapid sustained; unpredictable stress; chronic unpredictable; rvd1 rvd2 ... See more keywords
Molecular Dynamics Simulations Provide Insight into the Loading Efficiency of Pro-Resolving Lipid Mediators Resolvin D1 and D2 in Cell Membrane-Derived Nanovesicles.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00299
Abstract: Resolvins D1 and D2 (RvDs) are structural isomers and metabolites of docosahexaenoic acid, an omega-3 fatty acid, enzymatically produced in our body in response to acute inflammation or microbial invasion. Resolvins have been shown to… read more here.
Keywords: cell membrane; rvd1 rvd2; derived nanovesicles; membrane derived ... See more keywords
Lung Inflammation Resolution by RvD1 and RvD2 in a Receptor-Dependent Manner
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051527
Abstract: Inflammation resolution is an active process via specialized pro-resolving mediators (SPMs) to fight invading microbes and repair tissue injury. RvD1 and RvD2 are SPMs produced from DHA during inflammation responses and show a benefit in… read more here.
Keywords: inflammation resolution; inflammation; lung inflammation; rvd1 rvd2 ... See more keywords